1. Gene
  2. TMEM79 - transmembrane protein 79 Gene

TMEM79 - transmembrane protein 79 Gene

中文名称:跨膜蛋白 79

种属: Homo sapiens

同用名: MATT

基因 ID: 84283 | 基因类型: protein coding

关于 TMEM79

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,282,932-156,292,443 (from NCBI)

This gene has 7 transcripts (splice variants) and 259 orthologues. Biased expression in skin (RPKM 34.9), esophagus (RPKM 32.0) and 6 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与多个过程,包括上皮细胞成熟;建立皮肤屏障;和表皮发育的积极调节。预计在角质化上游或角化内起作用;角质层发育;和毛囊形态发生。预计位于细胞质中。预计在溶酶体膜和跨高尔基网络膜中具有活性。 [由基因组资源联盟提供,2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Predicted to act upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in lysosomal membrane and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM79 基因产物(1)

mRNA Protein Name
NM_032323.3 NP_115699.1 transmembrane protein 79
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
21516116 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

transmembrane protein 79

mattrin

TMEM79 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TMEM79 Q9BSE2 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra TMEM79 Q9BSE2 ABO Homo sapiens B0B1U2
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 ABO Homo sapiens B0B1U2
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 ABO Homo sapiens B0B1U2
Y2H Array
25416956
Intra TMEM79 Q9BSE2 SFTPC Homo sapiens P11686
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 SFTPC Homo sapiens P11686
Y2H Array
31515488
Intra TMEM79 Q9BSE2 SFTPC Homo sapiens P11686
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 TNMD Homo sapiens Q9H2S6
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 TNMD Homo sapiens Q9H2S6
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 TMPRSS4 Homo sapiens Q9NRS4-3
Y2H Array
25416956
Intra TMEM79 Q9BSE2 TMPRSS4 Homo sapiens Q9NRS4-3
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 TMPRSS4 Homo sapiens Q9NRS4
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 TMPRSS4 Homo sapiens Q9NRS4
Y2H Array
25416956
Intra TMEM79 Q9BSE2 TMPRSS4 Homo sapiens Q9NRS4
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 TEX264 Homo sapiens Q9Y6I9
Complementation
32296183
Intra TMEM79 Q9BSE2 TEX264 Homo sapiens Q9Y6I9
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 TEX264 Homo sapiens Q9Y6I9
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 TEX264 Homo sapiens Q9Y6I9
Y2H Array
25416956
Intra TMEM79 Q9BSE2 SERP1 Homo sapiens Q9Y6X1
Y2H Array
25416956
Intra TMEM79 Q9BSE2 SERP1 Homo sapiens Q9Y6X1
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 CYB5R3 Homo sapiens P00387
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 CYB5R3 Homo sapiens P00387
Y2H Array
32296183
Intra TMEM79 Q9BSE2 RPRM Homo sapiens Q9NS64
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 RPRM Homo sapiens Q9NS64
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 RPRM Homo sapiens Q9NS64
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 RPRM Homo sapiens Q9NS64
Y2H Array
25416956
Intra TMEM79 Q9BSE2 ARL13B Homo sapiens Q3SXY8
Y2H Array
32296183
Intra TMEM79 Q9BSE2 ARL13B Homo sapiens Q3SXY8
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 CLEC7A Homo sapiens Q9BXN2-6
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 TNMD Homo sapiens Q9H2S6-2
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 LPAR3 Homo sapiens Q9UBY5
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra TMEM79 Q9BSE2 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 GPRC5D Homo sapiens Q9NZD1
Y2H Array
32296183
Intra TMEM79 Q9BSE2 GPRC5D Homo sapiens Q9NZD1
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 GPRC5D Homo sapiens Q9NZD1
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra TMEM79 Q9BSE2 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra TMEM79 Q9BSE2 AMIGO1 Homo sapiens Q86WK6
Y2H Array
32296183
Intra TMEM79 Q9BSE2 AMIGO1 Homo sapiens Q86WK6
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 GCNT2 Homo sapiens Q8N0V5
Anti Tag CoIP
33961781
Intra TMEM79 Q9BSE2 GCNT2 Homo sapiens Q8N0V5
Anti Tag CoIP
28514442
Intra TMEM79 Q9BSE2 TMEM14C Homo sapiens Q9P0S9
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 RNF8 Homo sapiens O76064
Y2H Array
32296183
Intra TMEM79 Q9BSE2 RNF8 Homo sapiens O76064
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 RNF8 Homo sapiens O76064
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 CLEC7A Homo sapiens Q9BXN2
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 PELI2 Homo sapiens Q9HAT8
Validated Y2H
32296183
Intra TMEM79 Q9BSE2 PLP2 Homo sapiens Q04941
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 PLP2 Homo sapiens Q04941
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 PLP2 Homo sapiens Q04941
Y2H Array
25416956
Intra TMEM79 Q9BSE2 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra TMEM79 Q9BSE2 ZCCHC12 Homo sapiens Q6PEW1
Y2H Prey Pooling
32296183
Intra TMEM79 Q9BSE2 ZCCHC12 Homo sapiens Q6PEW1
Y2H Array
32296183
Intra TMEM79 Q9BSE2 TMEM100 Homo sapiens Q9NV29
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 TMEM100 Homo sapiens Q9NV29
Validated Y2H
25416956
Intra TMEM79 Q9BSE2 TMEM100 Homo sapiens Q9NV29
Y2H Array
25416956
Intra TMEM79 Q9BSE2 SEC22A Homo sapiens Q96IW7
Y2H Array
25416956
Intra TMEM79 Q9BSE2 SEC22A Homo sapiens Q96IW7
Y2H Prey Pooling
25416956
Intra TMEM79 Q9BSE2 SEC22A Homo sapiens Q96IW7
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Dermatitis

Eczema

Skin Inflammation

Inflammatory Dermatosis

Dermatitis, Atopic

Atopic Dermatitis

Atopic Eczema

Dermatitis, Atopic, Susceptibility To, 1

Atod

Eczema, Atopic

Dermatitis, Atopic 1

Allergic Dermatitis

Atopic Neurodermatitis

Besnier'S Prurigo

Dermatitis, Atopic, 1

Dermatitis Atopic

Eczema

Besnier Prurigo

Psoriasis 13

PSORS13

Psoriasis 13, Susceptibility To

Psoriasis

Psoriasis Vulgaris

Psoriasis Susceptibility 13

Pv

Psoriasis, Susceptibility To, Type 13

Ichthyosis Vulgaris

Ichthyosis Simplex

Dominant Congenital Ichthyosiform Erythroderma

Common Ichthyosis

Fish Scale Disease

VI

Ichthyoses

Congenital Ichthyosis

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus TMEM79 VGNC VGNC:66363
Mus musculus TMEM79 MGD MGI:1919163
Macaca mulatta TMEM79 VGNC VGNC:106521
Bos taurus TMEM79 VGNC VGNC:36112
Rattus norvegicus TMEM79 RGD RGD:1309886
Canis familiaris TMEM79 VGNC VGNC:47605