TMEM79 - transmembrane protein 79 Gene

中文名称：跨膜蛋白 79

种属: Homo sapiens

同用名: MATT

基因 ID: 84283 | 基因类型: protein coding

关于 TMEM79

Cytogenetic location: 1q22 Genomic coordinates (GRCh38): 1:156,282,932-156,292,443 (from NCBI)

This gene has 7 transcripts (splice variants) and 259 orthologues. Biased expression in skin (RPKM 34.9), esophagus (RPKM 32.0) and 6 other tissues.

功能概要

实现相同的蛋白质结合活性。预计参与多个过程，包括上皮细胞成熟；建立皮肤屏障；和表皮发育的积极调节。预计在角质化上游或角化内起作用；角质层发育；和毛囊形态发生。预计位于细胞质中。预计在溶酶体膜和跨高尔基网络膜中具有活性。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Predicted to be involved in several processes, including epithelial cell maturation; establishment of skin barrier; and positive regulation of epidermis development. Predicted to act upstream of or within cornification; cuticle development; and hair follicle morphogenesis. Predicted to be located in cytoplasm. Predicted to be active in lysosomal membrane and trans-Golgi network membrane. [provided by Alliance of Genome Resources, Apr 2022]

TMEM79 基因产物(1)

mRNA	Protein	Name
NM_032323.3	NP_115699.1	transmembrane protein 79

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables identical protein binding	IPI IPI: 通过物理相互作用推断	21516116	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

蛋白主名

其他名称

transmembrane protein 79

mattrin

TMEM79 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	TMEM79	Q9BSE2	LDLRAD1	Homo sapiens	Q5T700	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	LDLRAD1	Homo sapiens	Q5T700	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	ABO	Homo sapiens	B0B1U2	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	ABO	Homo sapiens	B0B1U2	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	ABO	Homo sapiens	B0B1U2	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	SFTPC	Homo sapiens	P11686	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	SFTPC	Homo sapiens	P11686	Y2H Array	31515488
种属内	TMEM79	Q9BSE2	SFTPC	Homo sapiens	P11686	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	TNMD	Homo sapiens	Q9H2S6	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	TNMD	Homo sapiens	Q9H2S6	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	TMPRSS4	Homo sapiens	Q9NRS4-3	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	TMPRSS4	Homo sapiens	Q9NRS4-3	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	TMPRSS4	Homo sapiens	Q9NRS4	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	TMPRSS4	Homo sapiens	Q9NRS4	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	TMPRSS4	Homo sapiens	Q9NRS4	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	TEX264	Homo sapiens	Q9Y6I9	Complementation	32296183
种属内	TMEM79	Q9BSE2	TEX264	Homo sapiens	Q9Y6I9	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	TEX264	Homo sapiens	Q9Y6I9	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	TEX264	Homo sapiens	Q9Y6I9	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	SERP1	Homo sapiens	Q9Y6X1	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	SERP1	Homo sapiens	Q9Y6X1	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	CYB5R3	Homo sapiens	P00387	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	CYB5R3	Homo sapiens	P00387	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	RPRM	Homo sapiens	Q9NS64	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	RPRM	Homo sapiens	Q9NS64	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	RPRM	Homo sapiens	Q9NS64	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	RPRM	Homo sapiens	Q9NS64	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	CLEC7A	Homo sapiens	Q9BXN2-6	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	TNMD	Homo sapiens	Q9H2S6-2	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	LPAR3	Homo sapiens	Q9UBY5	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	FNDC9	Homo sapiens	Q8TBE3	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	FNDC9	Homo sapiens	Q8TBE3	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	GPRC5D	Homo sapiens	Q9NZD1	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	GPRC5D	Homo sapiens	Q9NZD1	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	GPRC5D	Homo sapiens	Q9NZD1	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	CPLX4	Homo sapiens	Q7Z7G2	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	CPLX4	Homo sapiens	Q7Z7G2	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	FAM209A	Homo sapiens	Q5JX71	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	FAM209A	Homo sapiens	Q5JX71	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	AMIGO1	Homo sapiens	Q86WK6	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	AMIGO1	Homo sapiens	Q86WK6	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	GCNT2	Homo sapiens	Q8N0V5	Anti Tag CoIP	33961781
种属内	TMEM79	Q9BSE2	GCNT2	Homo sapiens	Q8N0V5	Anti Tag CoIP	28514442
种属内	TMEM79	Q9BSE2	TMEM14C	Homo sapiens	Q9P0S9	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	RNF8	Homo sapiens	O76064	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	RNF8	Homo sapiens	O76064	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	RNF8	Homo sapiens	O76064	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	CLEC7A	Homo sapiens	Q9BXN2	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	PELI2	Homo sapiens	Q9HAT8	Validated Y2H	32296183
种属内	TMEM79	Q9BSE2	PLP2	Homo sapiens	Q04941	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	PLP2	Homo sapiens	Q04941	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	PLP2	Homo sapiens	Q04941	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	COQ9	Homo sapiens	O75208	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	COQ9	Homo sapiens	O75208	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	ZCCHC12	Homo sapiens	Q6PEW1	Y2H Prey Pooling	32296183
种属内	TMEM79	Q9BSE2	ZCCHC12	Homo sapiens	Q6PEW1	Y2H Array	32296183
种属内	TMEM79	Q9BSE2	TMEM100	Homo sapiens	Q9NV29	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	TMEM100	Homo sapiens	Q9NV29	Validated Y2H	25416956
种属内	TMEM79	Q9BSE2	TMEM100	Homo sapiens	Q9NV29	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	SEC22A	Homo sapiens	Q96IW7	Y2H Array	25416956
种属内	TMEM79	Q9BSE2	SEC22A	Homo sapiens	Q96IW7	Y2H Prey Pooling	25416956
种属内	TMEM79	Q9BSE2	SEC22A	Homo sapiens	Q96IW7	Validated Y2H	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Dermatitis

Eczema	Skin Inflammation
Inflammatory Dermatosis

Dermatitis, Atopic

Atopic Dermatitis	Atopic Eczema
Dermatitis, Atopic, Susceptibility To, 1	Atod
Eczema, Atopic	Dermatitis, Atopic 1
Allergic Dermatitis	Atopic Neurodermatitis
Besnier'S Prurigo	Dermatitis, Atopic, 1
Dermatitis Atopic	Eczema
Besnier Prurigo

Psoriasis 13

PSORS13	Psoriasis 13, Susceptibility To
Psoriasis	Psoriasis Vulgaris
Psoriasis Susceptibility 13	Pv
Psoriasis, Susceptibility To, Type 13

Ichthyosis Vulgaris

Ichthyosis Simplex	Dominant Congenital Ichthyosiform Erythroderma
Common Ichthyosis	Fish Scale Disease
VI	Ichthyoses
Congenital Ichthyosis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS14742	TMEM79 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	TMEM79	VGNC	VGNC:66363
Mus musculus	TMEM79	MGD	MGI:1919163
Macaca mulatta	TMEM79	VGNC	VGNC:106521
Bos taurus	TMEM79	VGNC	VGNC:36112
Rattus norvegicus	TMEM79	RGD	RGD:1309886
Canis familiaris	TMEM79	VGNC	VGNC:47605

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