1. Gene
  2. SFTPC - surfactant protein C Gene

SFTPC - surfactant protein C Gene

中文名称:表面活性蛋白 C

种属: Homo sapiens

同用名: SP5; SP-C; PSP-C; SFTP2; SMDP2; BRICD6

基因 ID: 6440 | 基因类型: protein coding

关于 SFTPC

Cytogenetic location: 8p21.3 Genomic coordinates (GRCh38): 8:22,157,383-22,164,479 (from NCBI)

This gene has 13 transcripts (splice variants), 115 orthologues and is associated with 6 phenotypes. Restricted expression toward lung (RPKM 8558.2).

功能概要

该基因编码肺相关表面活性蛋白 C (SPC) ,这是一种极其疏水的表面活性蛋白,对出生后的肺功能和体内平衡至关重要。肺表面活性物质是一种表面活性脂蛋白复合物,由 90% 的脂质和 10% 的蛋白质组成,其中包括血浆蛋白和载脂蛋白 SPA、SPB、SPC 和 SPD。表面活性剂由肺泡细胞分泌,通过降低覆盖肺部的液体的表面张力来维持肺组织的稳定性。已确定该基因的多个突变会导致 2 型肺表面活性物质代谢功能障碍,也称为由于表面活性蛋白 C 缺乏引起的肺泡蛋白沉积症,并且与较大婴儿、儿童和成人的间质性肺病有关。已经鉴定出编码不同蛋白质亚型的可变剪接转录本变体。[RefSeq 提供,2010 年 2 月]

This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]

SFTPC 基因产物(14)

mRNA Protein Name
NM_001172357.2 NP_001165828.1 pulmonary surfactant-associated protein C isoform 2
NM_001172410.2 NP_001165881.1 pulmonary surfactant-associated protein C isoform 1 precursor
NM_001317778.2 NP_001304707.1 pulmonary surfactant-associated protein C isoform 2
NM_001317779.2 NP_001304708.1 pulmonary surfactant-associated protein C isoform 3
NM_001317780.2 NP_001304709.1 pulmonary surfactant-associated protein C isoform 2
NM_001385653.1 NP_001372582.1 pulmonary surfactant-associated protein C isoform 1 precursor
NM_001385654.1 NP_001372583.1 pulmonary surfactant-associated protein C isoform 1 precursor
NM_001385655.1 NP_001372584.1 pulmonary surfactant-associated protein C isoform 1 precursor
NM_001385656.1 NP_001372585.1 pulmonary surfactant-associated protein C isoform 2
NM_001385657.1 NP_001372586.1 pulmonary surfactant-associated protein C isoform 2
NM_001385658.1 NP_001372587.1 pulmonary surfactant-associated protein C isoform 2
NM_001385659.1 NP_001372588.1 pulmonary surfactant-associated protein C isoform 2
NM_001385660.1 NP_001372589.1 pulmonary surfactant-associated protein C isoform 3
NM_003018.4 NP_003009.2 pulmonary surfactant-associated protein C isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
19815549 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SFTPC 蛋白结构

SP_C-Propep

SP_C-Propep: Surfactant protein C, N terminal propeptide (1 - 93)

BRICHOS

BRICHOS: BRICHOS domain (94 - 197)

  • 0
  • 100
  • 197 a.a.
蛋白主名 其他名称

pulmonary surfactant-associated protein C

BRICHOS domain containing 6

SFTPC 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
SLC
25910212
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Prey Pooling
26871637
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Array
25910212
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Array
32296183
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Validated Y2H
25910212
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Validated Y2H
26871637
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Array
31515488
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Array
25416956
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Bait-Prey Pool
25910212
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Validated Y2H
32296183
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Array
25910212
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Array
26871637
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Array
25416956
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Bait-Prey Pool
25910212
Intra SFTPC P11686 TMEM79 Homo sapiens Q9BSE2
Y2H Array
32296183
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Validated Y2H
25910212
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Y2H Array
31515488
Intra SFTPC P11686 SFTPC Homo sapiens P11686
Validated Y2H
32296183
Intra SFTPC P11686 LSMEM2 Homo sapiens Q8N112
Y2H Array
32296183
Intra SFTPC P11686 LSMEM2 Homo sapiens Q8N112
Y2H Prey Pooling
32296183
Intra SFTPC P11686 LSMEM2 Homo sapiens Q8N112
Validated Y2H
32296183
Intra SFTPC P11686 BSCL2 Homo sapiens J3KQ12
Y2H Prey Pooling
32296183
Intra SFTPC P11686 BSCL2 Homo sapiens J3KQ12
Y2H Array
32296183
Intra SFTPC P11686 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
Intra SFTPC P11686 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
Intra SFTPC P11686 GPX8 Homo sapiens Q8TED1
Anti Tag CoIP
33961781
Intra SFTPC P11686 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205-2
SLC
25910212
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205-2
Validated Y2H
25910212
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205-2
Y2H Bait-Prey Pool
25910212
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205-2
Y2H Array
25910212
Intra SFTPC P11686 FNDC9 Homo sapiens Q8TBE3
Validated Y2H
32296183
Intra SFTPC P11686 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
Intra SFTPC P11686 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra SFTPC P11686 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra SFTPC P11686 HPN Homo sapiens P05981
Y2H Prey Pooling
32296183
Intra SFTPC P11686 HPN Homo sapiens P05981
Y2H Array
32296183
Intra SFTPC P11686 CD200R1 Homo sapiens Q8TD46-4
Y2H Prey Pooling
32296183
Intra SFTPC P11686 CD200R1 Homo sapiens Q8TD46-4
Y2H Array
32296183
Intra SFTPC P11686 CD200R1 Homo sapiens Q8TD46-4
Validated Y2H
32296183
Intra SFTPC P11686 SIGLEC9 Homo sapiens Q9Y336
Y2H Prey Pooling
32296183
Intra SFTPC P11686 SIGLEC9 Homo sapiens Q9Y336
Y2H Array
32296183
Intra SFTPC P11686 SIGLEC9 Homo sapiens Q9Y336
Validated Y2H
32296183
Intra SFTPC P11686 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra SFTPC P11686 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
Intra SFTPC P11686 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra SFTPC P11686 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra SFTPC P11686 MUC1 Homo sapiens P15941-11
Validated Y2H
32296183
Intra SFTPC P11686 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra SFTPC P11686 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra SFTPC P11686 GJA8 Homo sapiens P48165
Validated Y2H
32296183
Intra SFTPC P11686 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra SFTPC P11686 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra SFTPC P11686 CPLX4 Homo sapiens Q7Z7G2
Validated Y2H
32296183
Intra SFTPC P11686 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra SFTPC P11686 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra SFTPC P11686 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra SFTPC P11686 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
Intra SFTPC P11686 CLDN5 Homo sapiens O00501
Y2H Array
32296183
Intra SFTPC P11686 CLDN5 Homo sapiens O00501
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM106C Homo sapiens Q9BVX2
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM106C Homo sapiens Q9BVX2
Validated Y2H
32296183
Intra SFTPC P11686 TMEM106C Homo sapiens Q9BVX2
Y2H Array
32296183
Intra SFTPC P11686 IFNGR2 Homo sapiens P38484
Validated Y2H
32296183
Intra SFTPC P11686 IFNGR2 Homo sapiens P38484
Y2H Array
32296183
Intra SFTPC P11686 IFNGR2 Homo sapiens P38484
Y2H Prey Pooling
32296183
Intra SFTPC P11686 CXCL9 Homo sapiens Q07325
Validated Y2H
32296183
Intra SFTPC P11686 CXCL9 Homo sapiens Q07325
Y2H Prey Pooling
25416956
Intra SFTPC P11686 CXCL9 Homo sapiens Q07325
Validated Y2H
25416956
Intra SFTPC P11686 PVR Homo sapiens P15151
Y2H Array
32296183
Intra SFTPC P11686 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra SFTPC P11686 PVR Homo sapiens P15151
Anti Tag CoIP
33961781
Intra SFTPC P11686 PVR Homo sapiens P15151
Validated Y2H
32296183
Intra SFTPC P11686 SEC61G Homo sapiens P60059
Validated Y2H
25416956
Intra SFTPC P11686 CREB3 Homo sapiens O43889-2
Y2H Bait-Prey Pool
25910212
Intra SFTPC P11686 CREB3 Homo sapiens O43889-2
Validated Y2H
25910212
Intra SFTPC P11686 CREB3 Homo sapiens O43889-2
Y2H Array
25910212
Intra SFTPC P11686 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra SFTPC P11686 GOLM1 Homo sapiens Q8NBJ4
Validated Y2H
32296183
Intra SFTPC P11686 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205
Y2H Array
25416956
Intra SFTPC P11686 SYNE4 Homo sapiens Q8N205
Y2H Prey Pooling
25416956
Intra SFTPC P11686 PDZK1IP1 Homo sapiens Q13113
Y2H Prey Pooling
32296183
Intra SFTPC P11686 PDZK1IP1 Homo sapiens Q13113
Validated Y2H
32296183
Intra SFTPC P11686 PDZK1IP1 Homo sapiens Q13113
Y2H Array
32296183
Intra SFTPC P11686 TMEM139 Homo sapiens Q8IV31
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM139 Homo sapiens Q8IV31
Validated Y2H
32296183
Intra SFTPC P11686 TMEM139 Homo sapiens Q8IV31
Y2H Array
32296183
Intra SFTPC P11686 ICAM3 Homo sapiens P32942
Y2H Prey Pooling
32296183
Intra SFTPC P11686 ICAM3 Homo sapiens P32942
Validated Y2H
32296183
Intra SFTPC P11686 ICAM3 Homo sapiens P32942
Y2H Array
32296183
Intra SFTPC P11686 SMIM3 Homo sapiens Q9BZL3
Y2H Bait-Prey Pool
25910212
Intra SFTPC P11686 SMIM3 Homo sapiens Q9BZL3
Validated Y2H
25910212
Intra SFTPC P11686 SMIM3 Homo sapiens Q9BZL3
SLC
25910212
Intra SFTPC P11686 SMIM3 Homo sapiens Q9BZL3
Y2H Array
25910212
Intra SFTPC P11686 CD79A Homo sapiens P11912
Validated Y2H
32296183
Intra SFTPC P11686 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra SFTPC P11686 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra SFTPC P11686 SEC22A Homo sapiens Q96IW7
Y2H Prey Pooling
25416956
Intra SFTPC P11686 SEC22A Homo sapiens Q96IW7
Validated Y2H
32296183
Intra SFTPC P11686 KLRC1 Homo sapiens P26715
Y2H Prey Pooling
32296183
Intra SFTPC P11686 KLRC1 Homo sapiens P26715
Validated Y2H
32296183
Intra SFTPC P11686 KLRC1 Homo sapiens P26715
Y2H Array
32296183
Intra SFTPC P11686 TMEM30B Homo sapiens Q3MIR4
Y2H Prey Pooling
32296183
Intra SFTPC P11686 TMEM30B Homo sapiens Q3MIR4
Validated Y2H
32296183
Intra SFTPC P11686 TMEM30B Homo sapiens Q3MIR4
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Surfactant Metabolism Dysfunction, Pulmonary, 2

Interstitial Lung Disease Due To Surfactant Protein C Deficiency

SMDP2

Desquamative Interstitial Pneumonitis Due To Surfactant Protein C Deficiency

Pulmonary Alveolar Proteinosis, Congenital, 2

Chronic Respiratory Distress With Surfactant Metabolism Deficiency

Interstitial Lung Disease Due To Sp-C Deficiency

Pulmonary Surfactant Metabolism Dysfunction 2

Congenital Pulmonary Alveolar Proteinosis 2

Pap

Surfactant Metabolism Dysfunction, Pulmonary, Type 2

Interstitial Lung Disease 2

Idiopathic Pulmonary Fibrosis

Ipf

Fibrocystic Pulmonary Dysplasia

Pulmonary Fibrosis, Idiopathic

Pulmonary Fibrosis, Idiopathic, Susceptibility To

Cryptogenic Fibrosing Alveolitis

ILD2

Idiopathic Pulmonary Fibrosis, Familial

Fibrosing Alveolitis, Cryptogenic

Uip

Fibrosing Alveolitis

Interstitial Pneumonitis, Usual

Familial Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis, Chronic Form

Usual Interstitial Pneumonia

Fibrosing Alveolitis Cryptogenic

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis Familial

Interstitial Pneumonitis Usual

Fibrosis Idiopathic Pulmonary

Fibrosis, Pulmonary, Idiopathic

Hamman-Rich Syndrome

Chronic Idiopathic Pulmonary Fibrosis

Acute Interstitial Pneumonia

Interstitial Pulmonary Fibrosis

Ipf - [Idiopathic Pulmonary Fibrosis]

Idiopathic Lung Fibrosis

Fibrosing Lung Disease

Pulmonary Fibrosis Nos

Fibrosing Pneumonitis

Interstitial Lung Disease

Ild

Lung Diseases, Interstitial

Lung Diseases Interstitial

Interstitial Lung Diseases

Lung Disease

Lung Diseases

Disorder Of Lung

Abnormality Of The Lung

Pulmonary Alveolar Proteinosis
Respiratory Distress Syndrome In Premature Infants

Hyaline Membrane Disease

Infant Respiratory Distress Syndrome

Rds Of Prematurity

Hyaline Membrane Disease, Formerly

Infant Acute Respiratory Distress Syndrome

Infant Ards

Neonatal Respiratory Distress Syndrome

Respiratory Distress Syndrome, Infant

RDS

Rds In Prematurity

Respiratory Distress Syndrome, Newborn

Rds - Infants

Newborn Respiratory Distress Syndrome

Hyaline Membrane Disease

Respiratory Distress Syndrome Of Newborn

Neonatal Respiratory Distress

Hmd - Hyaline Membrane Disease

Neonatal Respiratory Distress Syndrome

Pulmonary Hyaline Membrane Disease

Pulmonary Hypoperfusion Syndrome Of Newborn

Respiratory Distress Syndrome, Newborn

Respiratory Distress Syndrome

Cardiorespiratory Distress Syndrome Of Newborn

Distress Respiratory Syndrome Newborn

Idiopathic Respiratory Distress Syndrome

Idiopathic Respiratory Distress Syndrome Of Newborn

Newborn Idiopathic Respiratory Distress Syndrome

Respiratory Distress Syndrome In Newborn

Rds - [Respiratory Distress Syndrome] Of Newborn

Newborn Cardiorespiratory Distress Syndrome

Skeletal Muscle Disease
Adult Respiratory Distress Syndrome

Acute Respiratory Distress Syndrome

Ards

Non-Cardiogenic Pulmonary Edema

Acute Lung Injury

Respiratory Distress Syndrome, Adult

Shock Lung

Acute Respiratory Distress

Respiratory Distress Syndrome

Adult Rds

Ali

Increased-Permeability Pulmonary Edema

Stiff Lung

Respiratory Distress Syndrome Adult

Pulmonary Fibrosis

Fibrosis Of Lung

Protein C Deficiency

Hereditary Thrombophilia Due To Protein C Deficiency

Proc Deficiency

Congenital Thrombotic Disease, Due To Protein C Deficiency

Respiratory Failure

Acute Respiratory Failure

Chronic Respiratory Failure

Respiratory Insufficiency

Acute-On-Chronic Respiratory Failure

Respiratory Disease

Acute And Chronic Respiratory Failure

Respiratory Insufficiency/Failure

Chronic Respiratory Disease

Pulmonary Valve Insufficiency

Chronic Disease Of Respiratory System

Respiration Disorders

Respiratory Tract Diseases

Lung Failure Nos

Pulmonary Failure

Arf - [Acute Respiratory Failure]

Acute Respiratory Insufficiency

Acute Pulmonary Insufficiency

Acute Respiration Failure

Chronic Respiration Failure

Neonatal Respiratory Failure

Respiratory Failure Of Newborn

Inadequate Pulmonary Ventilation Of Newborn

Newborn Lung Insufficiency

Newborn Pulmonary Function Inadequate

Newborn Pulmonary Insufficiency

Newborn Respiration Failure

Newborn Respiratory Insufficiency

Respiratory Insufficiency Syndrome Of Newborn

Interstitial Pneumonitis, Desquamative, Familial

Desquamative Interstitial Pneumonia

DIP

Pneumonitis, Desquamative Interstitial, Familial

Pneumonia, Desquamative Interstitial, Familial

Interstitial Lung Disease, Desquamative

Ild, Desquamative

Familial Desquamative Interstitial Pneumonitis

Rbild

Respiratory Bronchiolitis-Associated Interstitial Lung Disease

Respiratory Bronchiolitis Associated Interstitial Lung Disease

Lung Benign Neoplasm

Lung Neoplasms

Tumor Of The Lung

Lung Tumor

Pulmonary Interstitial Emphysema
Pulmonary Hypertension

Primary Pulmonary Hypertension

Hypertension Pulmonary

Hypertension, Pulmonary

Hypertension, Pulmonary, Primary

Idiopathic Pulmonary Hypertension

Idiopathic Pulmonary Arterial Hypertension

Pulmonary Htn - [Hypertension]

Pneumonia

Acute Pneumonia

Pneumonias

Infectious Pneumonia

Pn - [Pneumonia]

Lobar Pneumonia Nos

Multifocal Pneumonia

Orthostatic Pneumonia

Pneumonia Nos

Chronic Pneumonia Nos

Atypical Pneumonia

Passive Pneumonia

Purulent Pneumonia

Interstitial Lobar Pneumonia

Pneumonia, Unspecified

Pneumonia Due To Chlamydia

Pneumonia Due To Chlamydia Pneumoniae

Pneumonia Due To E. Coli

Escherichia Coli Lobar Pneumonia

Pneumonia Due To H. Influenzae

Pneumonia Due To Hemophilus Influenzae

Bronchopneumonia Due To H. Influenzae

Haemophilus Influenzae Lobar Pneumonia

Bronchopneumonia Due To Hemophilus Influenzae

Pseudomonal Pneumonia

Pseudomonas Pneumonia

Pseudomonas Lobar Pneumonia

Staphylococcal Pneumonia

Staphylococcus Pneumonia

Acute Staphylococcal Pneumonia

Staphylococcal Double Pneumonia

Staphylococcal Lobar Pneumonia

Staphylococcal Purulent Pneumonia

Staphylococcal Bronchopneumonia

Pneumococcal Pneumonia

Pneumococcus Pneumonia

Bronchopneumonia Due To S. Pneumoniae

Pneumococcal Lobar Pneumonia

Streptococcal Pneumoniae Pneumonia

Streptococcus Pneumoniae Lobar Pneumonia

Pyemic Pneumococcal Embolism With Pneumonia

Bronchopneumonia Due To Streptococcus Pneumoniae

Pneumonia Due To Streptococcus, Group B

Group B Streptococcal Pneumonia

Adenovirus Pneumonia

Adenoviral Pneumonia

Adenovirus Viral Pneumonia

Pneumonia Respiratory Syncytial Viral

Parainfluenza Viral Pneumonia

Parainfluenzal Pneumonia

Parainfluenza Virus Pneumonia

Human Metapneumovirus Pneumonia

Human Metapneumovirus Infection Resulting In Pneumonia

Pneumocystis Pneumonia

Plasma Cells Pneumonia

Nonspecific Interstitial Pneumonia

Nsip

Non-Specific Interstitial Pneumonia

Non-Specific Idiopathic Interstitial Pneumonia

Non-Specific Interstitial Pneumonia Nos

Pulmonary Emphysema
Myopathy

Muscular Diseases

Myopathies

Idiopathic Interstitial Pneumonia

Hamman-Rich Syndrome

Diffuse Idiopathic Pulmonary Fibrosis

Idiopathic Fibrosing Alveolitis

Ipf

Idiopathic Interstitial Pneumonias

Idiopathic Interstitial Pneumonia, Not Otherwise Specified

Pulmonary Fibrosis

Pulmonary Immaturity

Primary Atelectasis Of Newborn

Primary Atelectasis, In Perinatal Period

Primary Failure To Expand Terminal Respiratory Units

Immature Lungs

Primary Atelectasis

Pulmonary Immaturity Nos

Lung Lobe Hypoplasia, Associated With Short Gestation

Lung Nonexpansion

Premature Lungs

Pulmonary Hypoplasia Associated With Short Gestation

Failure Of Expansion Of Terminal Respiratory Units

Primary Atelectasis Of Fetus Or Newborn

Primary Atelectasis In Perinatal Period

Papillary Adenoma

Glandular Papilloma

Adenoma

Bronchial Benign Neoplasm

Bronchus Neoplasm

Neoplasm Of Bronchus

Bronchial Neoplasms

Bronchial Neoplasm

Large Cell Carcinoma

Carcinoma, Large Cell

Carcinoma Large Cell

Alveoli Adenoma

Alveolar Adenoma

Adenoma Of Alveoli

Adenoma Of The Alveoli

Adenosquamous Carcinoma

Adenosquamous Cell Carcinoma

Mixed Adenocarcinoma And Squamous Carcinoma

Carcinoma Adenosquamous

Carcinoma, Adenosquamous

Lung Adenoma

Adenoma Of Lung

Pulmonary Adenoma

Respiratory System Benign Neoplasm
Pulmonary Hemosiderosis

Idiopathic Pulmonary Hemosiderosis

Alveolar Hypoventilation Syndrome

Brown Induration

Brown Lung

Siderosis

Hemosiderosis, Pulmonary, With Deficiency Of Gamma-A Globulin

Byssinosis

Acute Interstitial Pneumonia

Acute Interstitial Pneumonitis

Hamman-Rich Syndrome

Accelerated Interstitial Pneumonia

Aip

Hamman-Rich Disease

Idiopathic Pulmonary Fibrosis, Acute Fatal Form

Idiopathic Pulmonary Fibrosis

Cystic Fibrosis

Mucoviscidosis

CF

Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

Cystic Fibrosis Lung Disease, Modifier Of

Cystic Fibrosis Of Pancreas

Fibrocystic Disease Of Pancreas

Cf - [Cystic Fibrosis]

Cystic Fibrosis Nos

Fibrocystic Disease

Fibrocystic Disease Of The Pancreas

Mucoviscidosis Of Pancreas

Nonproliferative Fibrocystic Disease

Pancreatic Cystic Fibrosis

Cryptogenic Organizing Pneumonia

Bronchiolitis Obliterans Organizing Pneumonia

Boop

Constrictive Bronchiolitis

Cryptogenic Organizing Pneumonitis

Cop

Bronchiolitis Obliterans Organising Pneumonia

Cryptogenic Organising Pneumonia

Cryptogenic Organising Pneumonitis

Idiopathic Bronchiolitis Obliterans With Organising Pneumonia

Idiopathic Bronchiolitis Obliterans With Organizing Pneumonia

Organizing Pneumonia

Idiopathic Boop

Idiopathic Bronchiolitis Obliterans Organizing Pneumonia

Organized Pneumonia

Lipid Pneumonia

Exogenous Lipoid Pneumonia

Lipoid Pneumonitis

Pneumonia, Lipid

Pneumonia Lipid

Lipoid Pneumonia

Diaphragm Disease

Abnormality Of The Diaphragm

Disease Of Diaphragm

Diaphragmatic Disorder

Disorder Of Diaphragm

Chronic Congestive Splenomegaly
Pulmonary Adenocarcinoma In Situ

Bronchioalveolar Carcinoma

Lung Cancer Susceptibility 3

Lung Adenocarcinoma

Adenocarcinoma Of Lung

LNCR3

Adenocarcinoma Of Lung, Susceptibility To

Bronchogenic Lung Adenocarcinoma

Nonsmall Cell Adenocarcinoma

Adenocarcinoma Lung

Lung Adenocarcinomas

Non-Small Cell Adenocarcinoma

Lung Carcinoma In Situ
Diaphragmatic Hernia, Congenital

Congenital Diaphragmatic Hernia

Diaphragmatic Hernia

Cdh

Congenital Diaphragmatic Defect

Hernia, Diaphragmatic

Dih

Hernia, Congenital Diaphragmatic

Hcd

Diaphragmatic Defect, Congenital

Diaphragm, Unilateral Agenesis Of

Hemidiaphragm, Agenesis Of

Diaphragmatic Hernia 1

Agenesis Of Hemidiaphragm

Unilateral Agenesis Of Diaphragm

Hernia Diaphragmatic

Hernia Diaphragmatic Congenital

Hernia, Diaphragmatic, Type 1

Hiatus Hernia

Oesophageal Hiatus Hernia

Paraoesophageal Hernia

Sliding Hiatus Hernia

Congenital Diaphragm Hernia

Congenital Diaphragm Defect With Hernia

Gross Congenital Diaphragm Defect

Asthma

Chronic Obstructive Asthma

Asthma, Diminished Response To Antileukotriene Treatment In

Bronchial Hyperreactivity

Asthma, Susceptibility To

Asthma, Bronchial

Asthma, Protection Against

Asthma, Nocturnal, Susceptibility To

Nocturnal Asthma

Asthma-Related Traits

Asthma-Related Traits, Susceptibility To

Asthma, Nocturnal

Chronic Obstructive Asthma With Acute Exacerbation

Chronic Obstructive Asthma With Status Asthmaticus

Exercise Induced Asthma

Exercise-Induced Asthma

Bronchial Asthma

Asthma, Exercise-Induced

Idiosyncratic Asthma

Unspecified Asthma With Acute Exacerbation

Asthma, Unspecified, With Stated Status Asthmaticus

Status Asthmaticus Nos

Acute Severe Asthma

Acute Severe Bronchial Asthma

Status Asthma

Status Post Asthmaticus

Hermansky-Pudlak Syndrome

Hps

Albinism With Hemorrhagic Diathesis And Pigmented Reticuloendothelial Cells

Hermanski-Pudlak Syndrome

Hermansky Pudlak Syndrome

Platelet Storage Pool Deficiency

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus SFTPC VGNC VGNC:34529
Rattus norvegicus SFTPC RGD RGD:3666
Mus musculus SFTPC MGD MGI:109517
Felis catus SFTPC VGNC VGNC:65067
Macaca mulatta SFTPC VGNC VGNC:84113
Canis familiaris SFTPC VGNC VGNC:54994