2. Gene
  3. TMEM100 - transmembrane protein 100 Gene

TMEM100 - transmembrane protein 100 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜蛋白 100

种属: Homo sapiens

基因 ID: 55273 | 基因类型: protein coding

关于 TMEM100

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:55,719,627-55,732,081 (from NCBI)

This gene has 6 transcripts (splice variants), 243 orthologues and 1 paralogue. Biased expression in lung (RPKM 28.4), fat (RPKM 14.1) and 10 other tissues.

功能概要

参与 BMP 信号通路。位于几种细胞成分中，包括内质网；核周;和细胞质的核周区。 [由基因组资源联盟提供，2022 年 4 月]

Involved in BMP signaling pathway. Located in several cellular components, including endoplasmic reticulum; perikaryon; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TMEM100 基因产物(2)

mRNA Protein Name
NM_001099640.2 NP_001093110.1 transmembrane protein 100
NM_018286.3 NP_060756.2 transmembrane protein 100
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in BMP signaling pathway IDA
IDA: 通过直接分析推断
22783020 GOA
involved in cellular response to BMP stimulus IDA
IDA: 通过直接分析推断
22783020 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum IDA
IDA: 通过直接分析推断
22783020 GOA
located in perikaryon IDA
IDA: 通过直接分析推断
23485812 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
22783020 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
23485812 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TMEM100 蛋白结构

PIRT

PIRT: Phosphoinositide-interacting protein family (12 - 133)

  • 0
  • 100
  • 134 a.a.
蛋白主名 其他名称

transmembrane protein 100

TMEM100 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
TMEM100 Q9NV29 RETREG3 Homo sapiens Q86VR2
Y2H Array
32296183
种属内
TMEM100 Q9NV29 RETREG3 Homo sapiens Q86VR2
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 JAGN1 Homo sapiens Q8N5M9
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 JAGN1 Homo sapiens Q8N5M9
Y2H Array
32296183
种属内
TMEM100 Q9NV29 IFNGR1 Homo sapiens P15260
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 IFNGR1 Homo sapiens P15260
Y2H Array
32296183
种属内
TMEM100 Q9NV29 NUP93 Homo sapiens Q8N1F7
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 NUP93 Homo sapiens Q8N1F7
Y2H Array
32296183
种属内
TMEM100 Q9NV29 RMDN3 Homo sapiens Q96TC7
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 RMDN3 Homo sapiens Q96TC7
Y2H Array
32296183
种属内
TMEM100 Q9NV29 CCDC57 Homo sapiens Q2TAC2-2
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 CCDC57 Homo sapiens Q2TAC2-2
Y2H Array
32296183
种属内
TMEM100 Q9NV29 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
种属内
TMEM100 Q9NV29 FNDC9 Homo sapiens Q8TBE3
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 FNDC9 Homo sapiens Q8TBE3
Y2H Array
32296183
种属内
TMEM100 Q9NV29 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 AQP6 Homo sapiens Q13520
Y2H Array
32296183
种属内
TMEM100 Q9NV29 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
TMEM100 Q9NV29 SLC30A4 Homo sapiens O14863
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 SLC30A4 Homo sapiens O14863
Y2H Array
32296183
种属内
TMEM100 Q9NV29 REEP1 Homo sapiens Q9H902
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 REEP1 Homo sapiens Q9H902
Y2H Array
32296183
种属内
TMEM100 Q9NV29 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 GJA8 Homo sapiens P48165
Y2H Array
32296183
种属内
TMEM100 Q9NV29 TMEM167B Homo sapiens Q9NRX6
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 TMEM167B Homo sapiens Q9NRX6
Y2H Array
32296183
种属内
TMEM100 Q9NV29 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
种属内
TMEM100 Q9NV29 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
种属内
TMEM100 Q9NV29 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
TMEM100 Q9NV29 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 SLC35A5 Homo sapiens Q9BS91
Y2H Array
32296183
种属内
TMEM100 Q9NV29 SLC35A5 Homo sapiens Q9BS91
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 TMEM130 Homo sapiens Q8N3G9
Y2H Array
32296183
种属内
TMEM100 Q9NV29 TMEM130 Homo sapiens Q8N3G9
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 RNF19B Homo sapiens Q6ZMZ0
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 RNF19B Homo sapiens Q6ZMZ0
Y2H Array
32296183
种属内
TMEM100 Q9NV29 STING1 Homo sapiens Q86WV6
Y2H Array
32296183
种属内
TMEM100 Q9NV29 STING1 Homo sapiens Q86WV6
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 CCDC57 Homo sapiens Q2TAC2
Validated Y2H
25416956
种属内
TMEM100 Q9NV29 LHFPL5 Homo sapiens Q8TAF8
Y2H Array
32296183
种属内
TMEM100 Q9NV29 LHFPL5 Homo sapiens Q8TAF8
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 COMT Homo sapiens P21964
Y2H Array
32296183
种属内
TMEM100 Q9NV29 COMT Homo sapiens P21964
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 CD33 Homo sapiens P20138
Y2H Array
32296183
种属内
TMEM100 Q9NV29 CD33 Homo sapiens P20138
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 EBP Homo sapiens Q15125
Y2H Array
32296183
种属内
TMEM100 Q9NV29 STX1A Homo sapiens Q16623
Y2H Array
32296183
种属内
TMEM100 Q9NV29 STX1A Homo sapiens Q16623
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 CLDN7 Homo sapiens O95471
Y2H Array
32296183
种属内
TMEM100 Q9NV29 F11R Homo sapiens Q9Y624
Y2H Array
32296183
种属内
TMEM100 Q9NV29 F11R Homo sapiens Q9Y624
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 F11R Homo sapiens Q9Y624
Validated Y2H
32296183
种属内
TMEM100 Q9NV29 VSIR Homo sapiens Q9H7M9
Y2H Array
32296183
种属内
TMEM100 Q9NV29 VSIR Homo sapiens Q9H7M9
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 MEOX2 Homo sapiens P50222
Y2H Array
25416956
种属内
TMEM100 Q9NV29 MEOX2 Homo sapiens P50222
Y2H Prey Pooling
25416956
种属内
TMEM100 Q9NV29 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
种属内
TMEM100 Q9NV29 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
种属内
TMEM100 Q9NV29 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Van Den Ende-Gupta Syndrome

VDEGS

Blepharophimosis, Arachnodactyly, And Congenital Contractures

Marden-Walker-Like Syndrome

Marden-Walker-Like Syndrome Without Psychomotor Retardation

Marden Walker Like Syndrome

Marden-Walker-Like Syndrome Without Psychmotor Retardation

Van Den Ende Gupta Syndrome

Marden Walker Like Syndrome Without Psychomotor Retardation

Blepharophimosis Arachnodactyly And Congenital Contractures
Hereditary Hemorrhagic Telangiectasia

Rendu-Osler-Weber Disease

Hht

Osler-Weber-Rendu Disease

Telangiectasia, Hereditary Hemorrhagic

Osler Hemorrhagic Telangiectasia Syndrome

Orw Disease

Osler Weber Rendu Syndrome

Osler-Rendu-Weber Disease

Osler-Weber-Rendu Syndrome

Rendu-Osler Disease

Telangiectasia Hereditary Hemorrhagic

Telangiectasia Hemorrhagic, Hereditary

Hht - [Hereditary Haemorrhagic Telangiectasia]

Osler Haemorrhagic Telangiectasia Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P10356 T100-Mut Inhibitor / 否
HY-RS14643 TMEM100 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus TMEM100 MGD MGI:1915138
Felis catus TMEM100 VGNC VGNC:66253
Rattus norvegicus TMEM100 RGD RGD:1560541
Canis familiaris TMEM100 VGNC VGNC:47443
Macaca mulatta TMEM100 VGNC VGNC:79521
Bos taurus TMEM100 VGNC VGNC:35941
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