2. Gene
  3. CYBC1 - cytochrome b-245 chaperone 1 Gene

CYBC1 - cytochrome b-245 chaperone 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：细胞色素 b-245 伴侣 1

种属: Homo sapiens

同用名: CGD5; Eros; C17orf62

基因 ID: 79415 | 基因类型: protein coding

关于 CYBC1

Cytogenetic location: 17q25.3 Genomic coordinates (GRCh38): 17:82,442,586-82,450,752 (from NCBI)

This gene has 51 transcripts (splice variants), 193 orthologues and is associated with 2 phenotypes. Ubiquitous expression in spleen (RPKM 26.0), lymph node (RPKM 25.5) and 25 other tissues.

功能概要

参与吞噬后的先天免疫反应和呼吸爆发。位于内质网。与慢性肉芽肿病有关。 [由基因组资源联盟提供，2022 年 4 月]

Involved in innate immune response and respiratory burst after phagocytosis. Located in endoplasmic reticulum. Implicated in chronic granulomatous disease. [provided by Alliance of Genome Resources, Apr 2022]

CYBC1 基因产物(7)

mRNA Protein Name
NM_001033046.4 NP_001028218.1 cytochrome b-245 chaperone 1 isoform a
NM_001100407.3 NP_001093877.1 cytochrome b-245 chaperone 1 isoform a
NM_001100408.3 NP_001093878.1 cytochrome b-245 chaperone 1 isoform b
NM_001193653.2 NP_001180582.1 cytochrome b-245 chaperone 1 isoform a
NM_001193654.2 NP_001180583.1 cytochrome b-245 chaperone 1 isoform a
NM_001193655.2 NP_001180584.1 cytochrome b-245 chaperone 1 isoform a
NM_001193657.2 NP_001180586.1 cytochrome b-245 chaperone 1 isoform a

CYBC1 蛋白结构

DUF4564

DUF4564: Domain of unknown function (DUF4564) (1 - 183)

  • 0
  • 100
  • 187 a.a.
蛋白主名 其他名称

cytochrome b-245 chaperone 1

essential for reactive oxygen species protein

CYBC1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CYBC1 Q9BQA9 SPN Homo sapiens P16150
Y2H Array
32296183
Intra CYBC1 Q9BQA9 SPN Homo sapiens P16150
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 NINJ2 Homo sapiens Q9NZG7
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 LXN Homo sapiens Q9BS40
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 CISD2 Homo sapiens Q8N5K1
Y2H Array
32296183
Intra CYBC1 Q9BQA9 CISD2 Homo sapiens Q8N5K1
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
Intra CYBC1 Q9BQA9 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 P2RX1 Homo sapiens P51575
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 P2RX1 Homo sapiens P51575
Y2H Array
32296183
Intra CYBC1 Q9BQA9 TMEM80 Homo sapiens Q96HE8
Y2H Array
32296183
Intra CYBC1 Q9BQA9 TMEM80 Homo sapiens Q96HE8
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 GPR151 Homo sapiens Q8TDV0
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 GPR151 Homo sapiens Q8TDV0
Y2H Array
32296183
Intra CYBC1 Q9BQA9 MFF Homo sapiens Q9GZY8-5
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
Intra CYBC1 Q9BQA9 STX2 Homo sapiens P32856-2
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 STX2 Homo sapiens P32856-2
Y2H Array
32296183
Intra CYBC1 Q9BQA9 AIG1 Homo sapiens Q9NVV5-2
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 AHNAK2 Homo sapiens Q8IVF2-3
Y2H Array
32296183
Intra CYBC1 Q9BQA9 AHNAK2 Homo sapiens Q8IVF2-3
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 TMPRSS2 Homo sapiens O15393-2
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 TMPRSS2 Homo sapiens O15393-2
Y2H Array
32296183
Intra CYBC1 Q9BQA9 APCDD1L Homo sapiens Q8NCL9
Y2H Array
32296183
Intra CYBC1 Q9BQA9 APCDD1L Homo sapiens Q8NCL9
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra CYBC1 Q9BQA9 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 NOX3 Homo sapiens Q9HBY0
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 NOX3 Homo sapiens Q9HBY0
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 NOX3 Homo sapiens Q9HBY0
Y2H Array
32296183
Intra CYBC1 Q9BQA9 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
Intra CYBC1 Q9BQA9 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra CYBC1 Q9BQA9 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 SLC35C2 Homo sapiens Q9NQQ7-3
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 SLC35C2 Homo sapiens Q9NQQ7-3
Y2H Array
32296183
Intra CYBC1 Q9BQA9 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra CYBC1 Q9BQA9 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra CYBC1 Q9BQA9 SHISA4 Homo sapiens Q96DD7
Y2H Array
32296183
Intra CYBC1 Q9BQA9 SHISA4 Homo sapiens Q96DD7
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
Intra CYBC1 Q9BQA9 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
Intra CYBC1 Q9BQA9 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 AQP8 Homo sapiens O94778
Y2H Array
32296183
Intra CYBC1 Q9BQA9 AQP8 Homo sapiens O94778
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 TSPAN12 Homo sapiens O95859
Y2H Array
32296183
Intra CYBC1 Q9BQA9 TSPAN12 Homo sapiens O95859
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra CYBC1 Q9BQA9 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra CYBC1 Q9BQA9 APOL2 Homo sapiens Q9BQE5
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 PEX12 Homo sapiens O00623
Y2H Array
32296183
Intra CYBC1 Q9BQA9 PEX12 Homo sapiens O00623
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 CLN6 Homo sapiens Q9NWW5
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 TMX2 Homo sapiens Q9Y320
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 TMX2 Homo sapiens Q9Y320
Y2H Array
32296183
Intra CYBC1 Q9BQA9 TMX2 Homo sapiens Q9Y320
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 TM4SF19 Homo sapiens Q96DZ7
Y2H Array
32296183
Intra CYBC1 Q9BQA9 TM4SF19 Homo sapiens Q96DZ7
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 PDZK1IP1 Homo sapiens Q13113
Y2H Array
32296183
Intra CYBC1 Q9BQA9 PDZK1IP1 Homo sapiens Q13113
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 COQ9 Homo sapiens O75208
Y2H Array
32296183
Intra CYBC1 Q9BQA9 COQ9 Homo sapiens O75208
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MGST3 Homo sapiens O14880
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 MGST3 Homo sapiens O14880
Y2H Array
32296183
Intra CYBC1 Q9BQA9 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra CYBC1 Q9BQA9 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra CYBC1 Q9BQA9 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
25416956
Intra CYBC1 Q9BQA9 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 KASH5 Homo sapiens Q8N6L0
Validated Y2H
25416956
Intra CYBC1 Q9BQA9 KASH5 Homo sapiens Q8N6L0
Y2H Array
25416956
Intra CYBC1 Q9BQA9 ERGIC3 Homo sapiens Q9Y282
Y2H Array
32296183
Intra CYBC1 Q9BQA9 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 INSIG2 Homo sapiens Q9Y5U4
Validated Y2H
32296183
Intra CYBC1 Q9BQA9 KIR2DL3 Homo sapiens P43628
Y2H Array
32296183
Intra CYBC1 Q9BQA9 KIR2DL3 Homo sapiens P43628
Y2H Prey Pooling
32296183
Intra CYBC1 Q9BQA9 ETS1 Homo sapiens P14921
TAP
20195357
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Granulomatous Disease, Chronic, Autosomal Recessive, 5

CGD5

Granulomatous Disease, Chronic, Due To Cybc1 Deficiency

Chronic Granulomatous Disease 5, Autosomal Recessive
Chronic Granulomatous Disease

Cgd

Granulomatous Disease, Chronic

Autosomal Recessive Chronic Granulomatous Disease

X-Linked Chronic Granulomatous Disease

Bridges-Good Syndrome

Congenital Dysphagocytosis

Quie Syndrome

Chronic Septic Granulomatosis

Chronic Granulomatous Disorder

Granulomatous Disease Chronic

Granulomatous Disease, Chronic, X-Linked
Hyperalphalipoproteinemia 1

Hyperalphalipoproteinemia

HALP1

Cetp Deficiency

Cholesterol-Ester Transfer Protein Deficiency

Familial Hyperalphalipoproteinemia

Cholesteryl Ester Transfer Protein Deficiency

Cept Deficiency

Cholesterol Ester Transfer Protein Deficiency
Lymphadenitis

Acute Lymphadenitis

Chronic Lymphadenitis

Adenitis

Chronic Adenitis

Acute Adenitis

Inflammation Of Lymph Node

Adenitis Nos

Inflammation Of Gland

Lymphatic Gland Inflammation

Lymph Gland Inflammation

Polyadenitis

Chronic Adenitis Of Any Lymph Node Except Mesenteric

Chronic Lymphadenitis Except Mesenteric

Chronic Non-Specific Lymphadenitis
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03426 CYBC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CYBC1 RGD RGD:1562022
Macaca mulatta CYBC1 VGNC VGNC:71601
Felis catus CYBC1 VGNC VGNC:98901
Canis familiaris CYBC1 VGNC VGNC:52590
Mus musculus CYBC1 MGD MGI:2384959
Bos taurus CYBC1 VGNC VGNC:52655
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