2. Gene
  3. UNC50 - unc-50 inner nuclear membrane RNA binding protein Gene

UNC50 - unc-50 inner nuclear membrane RNA binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：unc-50 内核膜 RNA 结合蛋白

种属: Homo sapiens

同用名: URP; GMH1; UNCL; HSD23; PDLs22

基因 ID: 25972 | 基因类型: protein coding

关于 UNC50

Cytogenetic location: 2q11.2 Genomic coordinates (GRCh38): 2:98,608,589-98,618,515 (from NCBI)

This gene has 6 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in thyroid (RPKM 28.7), testis (RPKM 24.9) and 25 other tissues.

功能概要

预测启用 RNA 结合活性。预计参与蛋白质定位到细胞表面。预测位于高尔基体和核内膜。预计是高尔基体膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable RNA binding activity. Predicted to be involved in protein localization to cell surface. Predicted to be located in Golgi apparatus and nuclear inner membrane. Predicted to be integral component of Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]

UNC50 基因产物(3)

mRNA Protein Name
NM_001330353.2 NP_001317282.1 protein unc-50 homolog isoform 2
NM_001330354.2 NP_001317283.1 protein unc-50 homolog isoform 1
NM_014044.7 NP_054763.2 protein unc-50 homolog isoform 3
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

UNC50 蛋白结构

UNC-50

UNC-50: UNC-50 family (30 - 256)

  • 0
  • 100
  • 200
  • 259 a.a.
蛋白主名 其他名称

protein unc-50 homolog

geal-6 membrane-associated high-copy suppressor 1

UNC50 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
UNC50 Q53HI1 SGPL1 Homo sapiens O95470
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 SGPL1 Homo sapiens O95470
Y2H Array
32296183
种属内
UNC50 Q53HI1 HSD17B11 Homo sapiens Q8NBQ5
Y2H Array
32296183
种属内
UNC50 Q53HI1 HSD17B11 Homo sapiens Q8NBQ5
Validated Y2H
32296183
种属内
UNC50 Q53HI1 HSD17B11 Homo sapiens Q8NBQ5
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 TMED8 Homo sapiens Q6PL24
Validated Y2H
32296183
种属内
UNC50 Q53HI1 TMED8 Homo sapiens Q6PL24
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 TMED8 Homo sapiens Q6PL24
Y2H Array
32296183
种属内
UNC50 Q53HI1 GPX8 Homo sapiens Q8TED1
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 GPX8 Homo sapiens Q8TED1
Y2H Array
32296183
种属内
UNC50 Q53HI1 GPX8 Homo sapiens Q8TED1
Validated Y2H
32296183
种属内
UNC50 Q53HI1 FITM2 Homo sapiens Q8N6M3
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 FITM2 Homo sapiens Q8N6M3
Y2H Array
32296183
种属内
UNC50 Q53HI1 FITM2 Homo sapiens Q8N6M3
Validated Y2H
32296183
种属内
UNC50 Q53HI1 MFF Homo sapiens Q9GZY8-5
Y2H Array
32296183
种属内
UNC50 Q53HI1 MFF Homo sapiens Q9GZY8-5
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 MFF Homo sapiens Q9GZY8-5
Validated Y2H
32296183
种属内
UNC50 Q53HI1 KCNJ6 Homo sapiens P48051
Y2H Array
32296183
种属内
UNC50 Q53HI1 KCNJ6 Homo sapiens P48051
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 AQP6 Homo sapiens Q13520
Y2H Array
32296183
种属内
UNC50 Q53HI1 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 GPR152 Homo sapiens Q8TDT2
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 GPR152 Homo sapiens Q8TDT2
Y2H Array
32296183
种属内
UNC50 Q53HI1 GPR152 Homo sapiens Q8TDT2
Validated Y2H
32296183
种属内
UNC50 Q53HI1 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
种属内
UNC50 Q53HI1 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 CLRN1 Homo sapiens P58418
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 CLRN1 Homo sapiens P58418
Y2H Array
32296183
种属内
UNC50 Q53HI1 TMEM167B Homo sapiens Q9NRX6
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 TMEM167B Homo sapiens Q9NRX6
Validated Y2H
32296183
种属内
UNC50 Q53HI1 TMEM167B Homo sapiens Q9NRX6
Y2H Array
32296183
种属内
UNC50 Q53HI1 HSD17B13 Homo sapiens Q7Z5P4
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 HSD17B13 Homo sapiens Q7Z5P4
Validated Y2H
32296183
种属内
UNC50 Q53HI1 HSD17B13 Homo sapiens Q7Z5P4
Y2H Array
32296183
种属内
UNC50 Q53HI1 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
种属内
UNC50 Q53HI1 FAM209A Homo sapiens Q5JX71
Validated Y2H
32296183
种属内
UNC50 Q53HI1 FAM209A Homo sapiens Q5JX71
Y2H Array
32296183
种属内
UNC50 Q53HI1 FAM209A Homo sapiens Q5JX71
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 ELOVL4 Homo sapiens Q9GZR5
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 ELOVL4 Homo sapiens Q9GZR5
Validated Y2H
32296183
种属内
UNC50 Q53HI1 ELOVL4 Homo sapiens Q9GZR5
Y2H Array
32296183
种属内
UNC50 Q53HI1 FFAR2 Homo sapiens O15552
Y2H Array
32296183
种属内
UNC50 Q53HI1 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 CLEC10A Homo sapiens Q8IUN9
Y2H Array
32296183
种属内
UNC50 Q53HI1 CLEC10A Homo sapiens Q8IUN9
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 CLEC10A Homo sapiens Q8IUN9
Validated Y2H
32296183
种属内
UNC50 Q53HI1 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
种属内
UNC50 Q53HI1 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 MFSD14B Homo sapiens Q5SR56
Validated Y2H
32296183
种属内
UNC50 Q53HI1 IFNGR2 Homo sapiens P38484
Y2H Array
32296183
种属内
UNC50 Q53HI1 IFNGR2 Homo sapiens P38484
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 EBP Homo sapiens Q15125
Y2H Array
32296183
种属内
UNC50 Q53HI1 DARS2 Homo sapiens Q6PI48
Validated Y2H
32296183
种属内
UNC50 Q53HI1 DARS2 Homo sapiens Q6PI48
Y2H Array
32296183
种属内
UNC50 Q53HI1 DARS2 Homo sapiens Q6PI48
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 SAR1A Homo sapiens Q9NR31
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 SAR1A Homo sapiens Q9NR31
Validated Y2H
32296183
种属内
UNC50 Q53HI1 SAR1A Homo sapiens Q9NR31
Y2H Array
32296183
种属内
UNC50 Q53HI1 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
种属内
UNC50 Q53HI1 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
种属内
UNC50 Q53HI1 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
种属内
UNC50 Q53HI1 MGST3 Homo sapiens O14880
Y2H Array
32296183
种属内
UNC50 Q53HI1 MGST3 Homo sapiens O14880
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 REEP4 Homo sapiens Q9H6H4
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 REEP4 Homo sapiens Q9H6H4
Y2H Array
32296183
种属内
UNC50 Q53HI1 REEP4 Homo sapiens Q9H6H4
Validated Y2H
32296183
种属内
UNC50 Q53HI1 ERGIC3 Homo sapiens Q9Y282
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 ERGIC3 Homo sapiens Q9Y282
Validated Y2H
32296183
种属内
UNC50 Q53HI1 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
种属内
UNC50 Q53HI1 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
种属内
UNC50 Q53HI1 TMEM234 Homo sapiens Q8WY98
Y2H Prey Pooling
32296183
种属内
UNC50 Q53HI1 TMEM234 Homo sapiens Q8WY98
Y2H Array
32296183
种属内
UNC50 Q53HI1 TMEM234 Homo sapiens Q8WY98
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Immunodeficiency 13

Idiopathic Cd4 Lymphopenia

IMD13

Icl

Immunodeficiency, Type 13
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15470 UNC50 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Mus musculus UNC50 MGD MGI:1914637
Felis catus UNC50 VGNC VGNC:66827
Macaca mulatta UNC50 VGNC VGNC:79004
Canis familiaris UNC50 VGNC VGNC:108222
Bos taurus UNC50 VGNC VGNC:36669
Rattus norvegicus UNC50 RGD RGD:621749
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