AQP10 - aquaporin 10 Gene

中文名称：水通道蛋白 10

种属: Homo sapiens

同用名: AQPA_HUMAN

基因 ID: 89872 | 基因类型: protein coding

关于 AQP10

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:154,321,093-154,325,325 (from NCBI)

This gene has 3 transcripts (splice variants), 390 orthologues and 11 paralogues. Biased expression in duodenum (RPKM 31.0) and small intestine (RPKM 22.0).

功能概要

该基因编码整合膜蛋白的 aquaglyceroporin 家族成员。这个家族的成员在吸收和排泄水的器官的上皮细胞中起透水通道的作用。这种蛋白质被证明具有水选择性通道的功能，还可以渗透甘油和尿素等中性溶质。[RefSeq 提供，2008 年 7 月]

This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq, Jul 2008]

AQP10 基因产物(1)

mRNA	Protein	Name
NM_080429.3	NP_536354.2	aquaporin-10

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables glycerol channel activity	IDA IDA: 通过直接分析推断	30420639	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA
enables water channel activity	IDA IDA: 通过直接分析推断	30420639	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in cellular response to acidic pH	IDA IDA: 通过直接分析推断	30420639	GOA
involved in glycerol transmembrane transport	IDA IDA: 通过直接分析推断	30420639	GOA
involved in protein homotetramerization	IDA IDA: 通过直接分析推断	30420639	GOA
involved in response to toxic substance	IDA IDA: 通过直接分析推断	17575980	GOA
involved in water transport	IDA IDA: 通过直接分析推断	30420639	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in plasma membrane	IDA IDA: 通过直接分析推断	30420639	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

AQP10 蛋白结构

MIP

0
100
200
301 a.a.

蛋白主名

其他名称

aquaporin-10

AQP-10

AQP10 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	AQP10	Q96PS8	LYVE1	Homo sapiens	Q9Y5Y7	Validated Y2H	32296183
Intra	AQP10	Q96PS8	LYVE1	Homo sapiens	Q9Y5Y7	Y2H Array	32296183
Intra	AQP10	Q96PS8	LYVE1	Homo sapiens	Q9Y5Y7	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	CISD2	Homo sapiens	Q8N5K1	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	PGRMC2	Homo sapiens	O15173	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	PGRMC2	Homo sapiens	O15173	Y2H Array	32296183
Intra	AQP10	Q96PS8	NEMP1	Homo sapiens	O14524-2	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	NEMP1	Homo sapiens	O14524-2	Y2H Array	32296183
Intra	AQP10	Q96PS8	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	AQP10	Q96PS8	PLP1	Homo sapiens	P60201-2	Y2H Array	32296183
Intra	AQP10	Q96PS8	PLP1	Homo sapiens	P60201-2	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	SCN3B	Homo sapiens	Q9NY72	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	SCN3B	Homo sapiens	Q9NY72	Validated Y2H	32296183
Intra	AQP10	Q96PS8	SCN3B	Homo sapiens	Q9NY72	Y2H Array	32296183
Intra	AQP10	Q96PS8	SSMEM1	Homo sapiens	Q8WWF3	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	SSMEM1	Homo sapiens	Q8WWF3	Y2H Array	32296183
Intra	AQP10	Q96PS8	TMEM167B	Homo sapiens	Q9NRX6	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	TMEM167B	Homo sapiens	Q9NRX6	Validated Y2H	32296183
Intra	AQP10	Q96PS8	TMEM167B	Homo sapiens	Q9NRX6	Y2H Array	32296183
Intra	AQP10	Q96PS8	CYBC1	Homo sapiens	Q9BQA9	Validated Y2H	32296183
Intra	AQP10	Q96PS8	CYBC1	Homo sapiens	Q9BQA9	Y2H Array	32296183
Intra	AQP10	Q96PS8	CYBC1	Homo sapiens	Q9BQA9	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	GPR37L1	Homo sapiens	O60883	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	GPR37L1	Homo sapiens	O60883	Y2H Array	32296183
Intra	AQP10	Q96PS8	PVR	Homo sapiens	P15151	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	PVR	Homo sapiens	P15151	Y2H Array	32296183
Intra	AQP10	Q96PS8	SAR1A	Homo sapiens	Q9NR31	Y2H Array	32296183
Intra	AQP10	Q96PS8	SAR1A	Homo sapiens	Q9NR31	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	SAR1A	Homo sapiens	Q9NR31	Validated Y2H	32296183
Intra	AQP10	Q96PS8	CREB3L1	Homo sapiens	Q96BA8	Y2H Array	32296183
Intra	AQP10	Q96PS8	CREB3L1	Homo sapiens	Q96BA8	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	MGST3	Homo sapiens	O14880	Y2H Array	32296183
Intra	AQP10	Q96PS8	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	ERGIC3	Homo sapiens	Q9Y282	Validated Y2H	32296183
Intra	AQP10	Q96PS8	ERGIC3	Homo sapiens	Q9Y282	Y2H Array	32296183
Intra	AQP10	Q96PS8	ERGIC3	Homo sapiens	Q9Y282	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	SYT2	Homo sapiens	Q8N9I0	Y2H Array	32296183
Intra	AQP10	Q96PS8	SYT2	Homo sapiens	Q8N9I0	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	KIR2DL3	Homo sapiens	P43628	Y2H Prey Pooling	32296183
Intra	AQP10	Q96PS8	KIR2DL3	Homo sapiens	P43628	Y2H Array	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Pompholyx

Dyshidrosis	Vesicular Eczema Of Hands And/Or Feet
Cheiropompholyx	Dyshydrotic Eczema
Eczema, Dyshidrotic	Vesicular Hand Eczema

Viral Gastritis

Fox-Fordyce Disease

Fox Fordyce Disease	Apocrine Miliaria
Fox-Fordyce Syndrome	Miliaria, Apocrine

Nephrogenic Diabetes Insipidus

Vasopressin-Resistant Diabetes Insipidus	Diabetes Insipidus, Nephrogenic
Diabetes Insipidus Nephrogenic	Congenital Nephrogenic Diabetes Insipidus
Adh Resistant Diabetes Insipidus	Diabetes Insipidus Nephrogenic X-Linked
Diabetes Insipidus Nephrogenic Type 1	Adh-Resistant Diabetes Insipidus
Diabetes Insipidus Renalis	Ndi
Renal Diabetes Insipidus	Familial Nephrogenic Diabetes
Antidiuretic-Hormone-Resistant Diabetes Insipidus	Adiuretin-Resistant Diabetes Insipidus
Ndi - [Nephrogenic Diabetes Insipidus]	Diabetes Tenuifluus
Adh - [Antidiuretic-Hormone] Resistant Diabetes Insipidus	Hereditary Nephrogenic Diabetes Insipidus
Familial Nephrogenic Diabetes Insipidus	Primary Nephrogenic Diabetes Insipidus

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS00872	AQP10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	AQP10	VGNC	VGNC:26044
Macaca mulatta	AQP10	VGNC	VGNC:69841
Rattus norvegicus	AQP10	RGD	RGD:1596307
Felis catus	AQP10	VGNC	VGNC:59859

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

AQP10 - aquaporin 10 Gene

关于 AQP10

功能概要

AQP10 基因产物(1)

AQP10 蛋白结构

AQP10 蛋白互作信息

关联疾病

直系同源

热门区域

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AQP10 - aquaporin 10 Gene

关于 AQP10

功能概要

AQP10 基因产物(1)

AQP10 蛋白结构

AQP10 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z