1. Gene
  2. SLC39A9 - solute carrier family 39 member 9 Gene

SLC39A9 - solute carrier family 39 member 9 Gene

中文名称:溶质载体家族 39 成员 9

种属: Homo sapiens

同用名: ZIP9; ZIP-9

基因 ID: 55334 | 基因类型: protein coding

关于 SLC39A9

Cytogenetic location: 14q24.1 Genomic coordinates (GRCh38): 14:69,398,384-69,462,390 (from NCBI)

This gene has 11 transcripts (splice variants) and 204 orthologues. Ubiquitous expression in thyroid (RPKM 15.0), kidney (RPKM 14.8) and 25 other tissues.

功能概要

预测可启用金属离子跨膜转运体活性。预计参与跨膜转运和锌离子转运。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable metal ion transmembrane transporter activity. Predicted to be involved in transmembrane transport and zinc ion transport. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

SLC39A9 基因产物(6)

mRNA Protein Name
NM_001252148.2 NP_001239077.1 zinc transporter ZIP9 isoform 2
NM_001252150.2 NP_001239079.1 zinc transporter ZIP9 isoform 3
NM_001252151.2 NP_001239080.1 zinc transporter ZIP9 isoform 4
NM_001252152.2 NP_001239081.1 zinc transporter ZIP9 isoform 4
NM_001330185.2 NP_001317114.1 zinc transporter ZIP9 isoform 5
NM_018375.5 NP_060845.2 zinc transporter ZIP9 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled receptor activity IDA
IDA: 通过直接分析推断
28219737 GOA
enables androgen binding IDA
IDA: 通过直接分析推断
28219737 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables zinc efflux transmembrane transporter activity IDA
IDA: 通过直接分析推断
19420709 GOA
enables zinc ion transmembrane transporter activity IDA
IDA: 通过直接分析推断
28219737 GOA
enables zinc ion transmembrane transporter activity IMP
IMP: 通过突变表型推断
25014355 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular zinc ion homeostasis IDA
IDA: 通过直接分析推断
19420709 GOA
involved in regulation of vascular endothelial cell proliferation IMP
IMP: 通过突变表型推断
34555425 GOA
involved in zinc ion transmembrane transport IDA
IDA: 通过直接分析推断
25014355 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial membrane IDA
IDA: 通过直接分析推断
25014355 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
34555425 GOA
located in nucleus IDA
IDA: 通过直接分析推断
25014355 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
25014355 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
25014355 GOA
located in trans-Golgi network IDA
IDA: 通过直接分析推断
19420709 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

SLC39A9 蛋白结构

Zip

Zip: ZIP Zinc transporter (131 - 301)

  • 0
  • 100
  • 200
  • 307 a.a.
蛋白主名 其他名称

zinc transporter ZIP9

ZRT/IRT-like protein 9

SLC39A9 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra SLC39A9 Q9NUM3 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 ELOVL5 Homo sapiens Q9NYP7
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 ELOVL5 Homo sapiens Q9NYP7
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 ELOVL5 Homo sapiens Q9NYP7
Validated Y2H
32296183
Intra SLC39A9 Q9NUM3 LNPEP Homo sapiens Q9UIQ6-2
Validated Y2H
32296183
Intra SLC39A9 Q9NUM3 SLC66A1 Homo sapiens Q6ZP29-3
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 SLC66A1 Homo sapiens Q6ZP29-3
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 SLC39A2 Homo sapiens Q9NP94
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 SLC39A2 Homo sapiens Q9NP94
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 AQP6 Homo sapiens Q13520
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 AQP6 Homo sapiens Q13520
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 TM4SF18 Homo sapiens Q96CE8
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 TM4SF18 Homo sapiens Q96CE8
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CRB3 Homo sapiens Q9BUF7-2
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CRB3 Homo sapiens Q9BUF7-2
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 SSMEM1 Homo sapiens Q8WWF3
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 SSMEM1 Homo sapiens Q8WWF3
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 EVI2B Homo sapiens P34910-2
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 EVI2B Homo sapiens P34910-2
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 GPR101 Homo sapiens Q96P66
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 GPR101 Homo sapiens Q96P66
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CPLX4 Homo sapiens Q7Z7G2
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CPLX4 Homo sapiens Q7Z7G2
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 TRHR Homo sapiens P34981
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 TRHR Homo sapiens P34981
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 SLC10A6 Homo sapiens Q3KNW5
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 SLC10A6 Homo sapiens Q3KNW5
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CERS3 Homo sapiens Q8IU89
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CERS3 Homo sapiens Q8IU89
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CBARP Homo sapiens Q8N350-4
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CBARP Homo sapiens Q8N350-4
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 APH1A Homo sapiens Q96BI3
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 APH1A Homo sapiens Q96BI3
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 TMEM140 Homo sapiens Q9NV12
Validated Y2H
32296183
Intra SLC39A9 Q9NUM3 HERPUD2 Homo sapiens Q9BSE4
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 HERPUD2 Homo sapiens Q9BSE4
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 MFSD14B Homo sapiens Q5SR56
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 MFSD14B Homo sapiens Q5SR56
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 MANBAL Homo sapiens Q9NQG1
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 MANBAL Homo sapiens Q9NQG1
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 MFSD5 Homo sapiens Q6N075
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 MFSD5 Homo sapiens Q6N075
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 SLC7A1 Homo sapiens P30825
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 SLC7A1 Homo sapiens P30825
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 CREB3L3 Homo sapiens Q68CJ9
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 CREB3L3 Homo sapiens Q68CJ9
Y2H Prey Pooling
32296183
Intra SLC39A9 Q9NUM3 HTR2C Homo sapiens P28335
Y2H Array
32296183
Intra SLC39A9 Q9NUM3 HTR2C Homo sapiens P28335
Y2H Prey Pooling
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Bos taurus SLC39A9 VGNC VGNC:34869
Mus musculus SLC39A9 MGD MGI:1914820
Rattus norvegicus SLC39A9 RGD RGD:1311236
Canis familiaris SLC39A9 VGNC VGNC:46408
Felis catus SLC39A9 VGNC VGNC:65364
Macaca mulatta SLC39A9 VGNC VGNC:77523