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  2. GPR101 - G protein-coupled receptor 101 Gene

GPR101 - G protein-coupled receptor 101 Gene

中文名称:G 蛋白偶联受体 101

种属: Homo sapiens

同用名: GPCR6; PAGH2; PITA2

基因 ID: 83550 | 基因类型: protein coding

关于 GPR101

Cytogenetic location: Xq26.3 Genomic coordinates (GRCh38): X:137,023,929-137,033,995 (from NCBI)

This gene has 1 transcript (splice variant), 152 orthologues, 18 paralogues and is associated with 3 phenotypes.

功能概要

该基因编码的蛋白质是一种功能未知的孤儿 G 蛋白偶联受体。编码的蛋白质是蛋白质家族的成员,该蛋白质家族包含七个跨膜结构域并通过异三聚体 G 蛋白转导细胞外信号。[RefSeq 提供,2011 年 9 月]

The protein encoded by this gene is an orphan G protein-coupled receptor of unknown function. The encoded protein is a member of a family of proteins that contain seven transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. [provided by RefSeq, Sep 2011]

GPR101 基因产物(1)

mRNA Protein Name
NM_054021.2 NP_473362.1 probable G-protein coupled receptor 101
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of receptor complex IDA
IDA: 通过直接分析推断
23382219 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GPR101 蛋白结构

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (48 - 454)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 508 a.a.
蛋白主名 其他名称

probable G-protein coupled receptor 101

GPR101 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra GPR101 Q96P66 NDUFB11 Homo sapiens Q9NX14
Validated Y2H
32296183
Intra GPR101 Q96P66 DERL3 Homo sapiens Q96Q80
Validated Y2H
32296183
Intra GPR101 Q96P66 AGPAT4 Homo sapiens Q9NRZ5
Validated Y2H
32296183
Intra GPR101 Q96P66 SLC39A9 Homo sapiens Q9NUM3
Validated Y2H
32296183
Intra GPR101 Q96P66 TMEM147 Homo sapiens Q9BVK8
Validated Y2H
32296183
Intra GPR101 Q96P66 UNC93B1 Homo sapiens Q9H1C4
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pituitary Adenoma 2, Growth Hormone-Secreting

PITA2

Acromegaly Due To Pituitary Adenoma 2

Acromegaly, X-Linked

Growth Hormone Secreting Pituitary Adenoma 2

Pituitary Adenoma, Growth Hormone-Secreting, 2

Pituitary Adenoma 2, Gh-Secreting

Gh-Secreting Pituitary Adenoma 2

X-Linked Acromegaly

Adenoma, Pituitary, Growth Hormone-Secreting, Type 2

Acromegaly

Gigantism

Growth Hormone Excess

Pituitary Giant

Somatotroph Adenoma

Growth Hormone-Secreting Pituitary Adenoma

Lissencephaly, X-Linked, 2

X-Linked Lissencephaly With Abnormal Genitalia

Hydranencephaly With Abnormal Genitalia

Xlag

Xlisg

X-Linked Lissencephaly With Ambiguous Genitalia

LISX2

Lissencephaly, X-Linked 2

X-Linked Lissencephaly 2

X-Linked Lissencephaly-Corpus Callosum Agenesis-Genital Anomalies Syndrome

Xlag Syndrome

Lissencephaly, X-Linked, With Ambiguous Genitalia

Xlis2

X-Linked Lissencephaly - Agenesis Of The Corpus Callosum - Genital Anomalies

X-Linked Lissencephaly-Agenesis Of The Corpus Callosum-Genital Anomalies Syndrome

Xlag Syndrome

Lissencephaly X-Linked With Ambiguous Genitalia

Lissencephaly, X-Linked, Type 2

Chromosome Xq26.3 Duplication Syndrome

Thrombophilia, X-Linked, Due To Factor Ix Defect

THPH8

Deep Venous Thrombosis, Protection Against

X-Linked Thrombophilia Due To Factor Ix Defect

Thrombophilia, X-Linked, Due To Factor 9 Defect

Thrombophilia 8, X-Linked, Due To Factor Ix Defect

Multiple Endocrine Neoplasia, Type Iv

Multiple Endocrine Neoplasia Type 4

MEN4

Multiple Endocrine Neoplasia 4

Neoplasia, Endocrine, Multiple, Type Iv

Pituitary Cancer

Pituitary Carcinoma

Malignant Pituitary Neoplasm

Malignant Tumor Of Pituitary Gland

Neoplasm Of Pituitary Gland

Pituitary Gland Cancer

Pituitary Gland Neoplasm

Pituitary Neoplasm

Carcinoma Of The Pituitary Gland

Neoplasm Of The Pituitary Gland

Pituitary Neoplasms

Malignant Neoplasm Of Pituitary Gland

Syndromic X-Linked Intellectual Disability Shashi Type

Mental Retardation, X-Linked, Syndromic 11, Shashi Type

Mrxs11

Shashi X-Linked Mental Retardation Syndrome

Smrxs

Syndromic X-Linked Intellectual Disability Type 11

X-Linked Mental Retardation Shashi Type

Mental Retardation, X-Linked, Syndromic 11

Hormone Producing Pituitary Cancer

Growth Hormone Producing Pituitary Tumor

Pituitary Tumors, Hormone Producing

Somatotropinoma

Growth Hormone-Producing Pituitary Gland Neoplasm

Dicer1 Syndrome

Pleuro-Pulmonary Blastoma Familial Tumor Susceptibility Syndrome

Pleuropulmonary Blastoma Familial Tumor Susceptibility Syndrome

Ppb Familial Tumor Susceptibility Syndrome

Dicer1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome

Pleuro-Pulmonary Blastoma Familial Tumor Susceptibility

Dicer1-Related Pleuropulmonary Blastoma

Pleuropulmonary Blastoma Familial Tumor And Dysplasia Syndrome

Pleuropulmonary Blastoma Family Tumor Susceptibility Syndrome

Ppbftds

Doid:0081063

Tsh Producing Pituitary Tumor

Thyrotroph Adenoma

Tsh Producing Pituitary Tumour

Tsh Secreting Adenoma Of The Pituitary

Tsh Secreting Tumor Of Pituitary

Tsh Secreting Tumour Of Pituitary

Tsh-Secreting Pituitary Adenoma

Pituitary Thyrotrophic Adenoma

Tsh-Oma

Thyroid Stimulating Hormone-Secreting Pituitary Adenoma

Thyroid Stimulating Hormone-Producing Pituitary Tumor

Carney Complex Variant

Carney Complex

Carney Syndrome

Carney Complex, Type 1

Lamb Syndrome

Name Syndrome

Myxoma-Spotty Pigmentation-Endocrine Overactivity Syndrome

Carney Complex - Trismus - Pseudocamptodactyly Syndrome

Carney Complex, Type 2

Car

Cnc1

Carney Myxoma-Endocrine Complex

Myxoma - Spotty Pigmentation - Endocrine Overactivity

Myxoma, Spotty Pigmentation, And Endocrine Overactivity

Lamb - Lentigines, Atrial Myxoma, Mucocutaneous Myoma, Blue Nevus Syndrome

Name - Nevi, Atrial Myxoma, Skin Myxoma, Ephelides Syndrome

Carney Complex-Trismus-Pseudocamptodactyly Syndrome

CACOV

Hyperpituitarism
Melanotic Neurilemmoma

Melanotic Schwannoma

Pigmented Neurilemmoma

Pigmented Schwannoma

Pituitary Infarct

Pituitary Infarction

Mccune-Albright Syndrome

Mass Syndrome

Polyostotic Fibrous Dysplasia

MAS

Fibrous Dysplasia Of Bone

Albright Syndrome

Mass Phenotype

Overlap Connective Tissue Disease

Mccune Albright Syndrome

Osteitis Fibrosa Disseminata

OCTD

Albright'S Disease

Pfd

Pofd

Albright'S Syndrome

Mccune-Albright Syndrome, Somatic, Mosaic

Albright'S Disease Of Bone

Albright'S Syndrome With Precocious Puberty

Albright-Mccune-Sternberg Syndrome

Albright-Sternberg Syndrome

Fibrous Dysplasia With Pigmentary Skin Changes And Precocious Puberty

Gonadotropin-Independent Female-Limited Sexual Precocity

Fibrous Dysplasia Polyostotic

Fibrous Dysplasia, Polyostotic

Pelvic Lipomatosis

Excess Of Mature Unencapsulated Fatty Tissue In The Pelvis

Functioning Pituitary Adenoma

Secretory Adenoma Of The Pituitary Gland

Endocrine Active Pituitary Adenoma

Secreting Pituitary Adenoma

Pituitary Adenoma, Functioning

Growth Hormone Secreting Pituitary Adenoma

Somatotroph Adenoma

Growth Hormone-Secreting Pituitary Adenoma

Growth Hormone Producing Adenoma Of The Pituitary

Growth Hormone Secreting Adenoma Of Pituitary

Myostatin-Related Muscle Hypertrophy

Mslhp

Muscle Hypertrophy Syndrome

Pituitary Gland Disease

Pituitary Diseases

Pituitary Dysfunction

Pituitary Disease

Pituitary Deficiency

Pituitary Disorders

Primary Pigmented Nodular Adrenocortical Disease

Ppnad

Primary Pigmented Nodular Adrenal Dysplasia

Pigmented Nodular Adrenocortical Disease, Primary, 2

Pigmented Nodular Adrenocortical Disease, Primary, 1

Multiple Endocrine Neoplasia, Type I

Multiple Endocrine Neoplasia Type 1

MEN1

Wermer Syndrome

Multiple Endocrine Neoplasia 1

Multiple Endocrine Neoplasia, Type 1

Men I

Endocrine Adenomatosis, Multiple

Mea I

Men Type I

Wermer'S Syndrome

Men1 Syndrome

Multiple Endocrine Adenomatosis

Endocrine Adenomatosis Multiple

Men 1

Familial Multiple Endocrine Neoplasia Type I

Neoplasia, Endocrine, Multiple, Type 1

Multiple Endocrine Neoplasia

Lissencephaly

Pachygyria

Broad Gyri Of Cerebrum

Large Gyri Of Cerebrum

Macrogyria

Congenital Nervous System Abnormality

Congenital Neurologic Anomaly

Congenital Nervous System Disorder

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus GPR101 MGD MGI:2685211
Rattus norvegicus GPR101 RGD RGD:1564196
Canis familiaris GPR101 VGNC VGNC:41391
Macaca mulatta GPR101 VGNC VGNC:72944
Bos taurus GPR101 VGNC VGNC:29543