2. Gene
  3. TMEM147 - transmembrane protein 147 Gene

TMEM147 - transmembrane protein 147 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：跨膜蛋白 147

种属: Homo sapiens

同用名: NEDFLPH; NIFIE14

基因 ID: 10430 | 基因类型: protein coding

关于 TMEM147

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:35,545,626-35,547,526 (from NCBI)

This gene has 9 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in kidney (RPKM 36.7), thyroid (RPKM 34.7) and 25 other tissues.

功能概要

启用核糖体结合活性。位于内质网膜上。部分含蛋白质复合物。 [由基因组资源联盟提供，2022 年 4 月]

Enables ribosome binding activity. Located in endoplasmic reticulum membrane. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2022]

TMEM147 基因产物(3)

mRNA Protein Name
NM_001242597.2 NP_001229526.1 transmembrane protein 147 isoform 2
NM_001242598.2 NP_001229527.1 transmembrane protein 147 isoform 3
NM_032635.4 NP_116024.1 transmembrane protein 147 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
14667819 GOA
enables ribosome binding IDA
IDA: 通过直接分析推断
32820719 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in multi-pass transmembrane protein insertion into ER membrane IDA
IDA: 通过直接分析推断
36261522 GOA
involved in protein localization to nuclear inner membrane IDA
IDA: 通过直接分析推断
32694168 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
36044892 GOA
located in endoplasmic reticulum membrane IDA
IDA: 通过直接分析推断
20538592 GOA
part of multi-pass translocon complex IDA
IDA: 通过直接分析推断
36261522 GOA
located in nuclear membrane IDA
IDA: 通过直接分析推断
32694168 GOA
part of protein-containing complex IDA
IDA: 通过直接分析推断
20538592 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TMEM147 蛋白结构

DUF2053

DUF2053: Predicted membrane protein (DUF2053) (2 - 158)

  • 0
  • 100
  • 200
  • 224 a.a.
蛋白主名 其他名称

transmembrane protein 147

protein NIFIE 14

TMEM147 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra TMEM147 Q9BVK8 SHISA3 Homo sapiens A0PJX4
Y2H Array
32296183
Intra TMEM147 Q9BVK8 SHISA3 Homo sapiens A0PJX4
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 LDLRAD1 Homo sapiens Q5T700
Y2H Array
31515488
Intra TMEM147 Q9BVK8 LDLRAD1 Homo sapiens Q5T700
Validated Y2H
25416956
Intra TMEM147 Q9BVK8 LDLRAD1 Homo sapiens Q5T700
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 LDLRAD1 Homo sapiens Q5T700
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TMEM248 Homo sapiens Q9NWD8
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 TMEM248 Homo sapiens Q9NWD8
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TMEM248 Homo sapiens Q9NWD8
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 RMDN3 Homo sapiens Q96TC7
Y2H Array
32296183
Intra TMEM147 Q9BVK8 RMDN3 Homo sapiens Q96TC7
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 DPM3 Homo sapiens Q9P2X0-2
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 DPM3 Homo sapiens Q9P2X0-2
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 DPM3 Homo sapiens Q9P2X0-2
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TMEM237 Homo sapiens Q96Q45-2
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TMEM237 Homo sapiens Q96Q45-2
Y2H Array
32296183
Intra TMEM147 Q9BVK8 SLC13A4 Homo sapiens Q9UKG4
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SLC13A4 Homo sapiens Q9UKG4
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 SLC13A4 Homo sapiens Q9UKG4
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR61 Homo sapiens Q9BZJ8
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 GPR61 Homo sapiens Q9BZJ8
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR61 Homo sapiens Q9BZJ8
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SLC12A7 Homo sapiens Q9Y666-2
Y2H Array
32296183
Intra TMEM147 Q9BVK8 SLC12A7 Homo sapiens Q9Y666-2
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SLC12A7 Homo sapiens Q9Y666-2
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Array
32296183
Intra TMEM147 Q9BVK8 PDCD1LG2 Homo sapiens Q9BQ51
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 MUC1 Homo sapiens P15941-11
Y2H Array
32296183
Intra TMEM147 Q9BVK8 MUC1 Homo sapiens P15941-11
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CLRN1 Homo sapiens P58418
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CLRN1 Homo sapiens P58418
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 ENPP4 Homo sapiens Q9Y6X5
Y2H Array
32296183
Intra TMEM147 Q9BVK8 ENPP4 Homo sapiens Q9Y6X5
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 ENPP4 Homo sapiens Q9Y6X5
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 GJA8 Homo sapiens P48165
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GJA8 Homo sapiens P48165
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 LEUTX Homo sapiens A8MZ59
Y2H Array
32296183
Intra TMEM147 Q9BVK8 LEUTX Homo sapiens A8MZ59
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 LHFPL2 Homo sapiens Q6ZUX7
Y2H Array
32296183
Intra TMEM147 Q9BVK8 LHFPL2 Homo sapiens Q6ZUX7
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 IL3RA Homo sapiens P26951
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 IL3RA Homo sapiens P26951
Y2H Array
32296183
Intra TMEM147 Q9BVK8 IL3RA Homo sapiens P26951
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 GPR101 Homo sapiens Q96P66
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 GPR101 Homo sapiens Q96P66
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR42 Homo sapiens O15529
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR42 Homo sapiens O15529
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TMEM52B Homo sapiens Q4KMG9
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TMEM52B Homo sapiens Q4KMG9
Y2H Array
32296183
Intra TMEM147 Q9BVK8 SUSD3 Homo sapiens Q96L08
Y2H Array
32296183
Intra TMEM147 Q9BVK8 SUSD3 Homo sapiens Q96L08
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TEX29 Homo sapiens Q8N6K0
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TEX29 Homo sapiens Q8N6K0
Y2H Array
32296183
Intra TMEM147 Q9BVK8 RNF185 Homo sapiens Q96GF1
Y2H Array
32296183
Intra TMEM147 Q9BVK8 RNF185 Homo sapiens Q96GF1
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TSPAN12 Homo sapiens O95859
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TSPAN12 Homo sapiens O95859
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 FFAR2 Homo sapiens O15552
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 FFAR2 Homo sapiens O15552
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CXCR2 Homo sapiens P25025
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CXCR2 Homo sapiens P25025
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR37L1 Homo sapiens O60883
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GPR37L1 Homo sapiens O60883
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 ABHD16A Homo sapiens O95870
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 ABHD16A Homo sapiens O95870
Y2H Array
32296183
Intra TMEM147 Q9BVK8 EBP Homo sapiens Q15125
Y2H Array
32296183
Intra TMEM147 Q9BVK8 EBP Homo sapiens Q15125
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 PVR Homo sapiens P15151
Y2H Array
32296183
Intra TMEM147 Q9BVK8 PVR Homo sapiens P15151
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SLC10A1 Homo sapiens Q14973
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SLC10A1 Homo sapiens Q14973
Y2H Array
32296183
Intra TMEM147 Q9BVK8 MTIF3 Homo sapiens Q9H2K0
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 MTIF3 Homo sapiens Q9H2K0
Y2H Array
32296183
Intra TMEM147 Q9BVK8 MTIF3 Homo sapiens Q9H2K0
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 PACC1 Homo sapiens Q9H813
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 PACC1 Homo sapiens Q9H813
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 PACC1 Homo sapiens Q9H813
Y2H Array
32296183
Intra TMEM147 Q9BVK8 EFNA4 Homo sapiens P52798
Y2H Array
32296183
Intra TMEM147 Q9BVK8 EFNA4 Homo sapiens P52798
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CD40 Homo sapiens P25942
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CD40 Homo sapiens P25942
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TACR1 Homo sapiens P25103
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TACR1 Homo sapiens P25103
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CREB3L1 Homo sapiens Q96BA8
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CREB3L1 Homo sapiens Q96BA8
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CREB3L1 Homo sapiens Q96BA8
Y2H Array
31515488
Intra TMEM147 Q9BVK8 GOLM1 Homo sapiens Q8NBJ4
Y2H Array
32296183
Intra TMEM147 Q9BVK8 GOLM1 Homo sapiens Q8NBJ4
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 SYNE4 Homo sapiens Q8N205
Validated Y2H
25416956
Intra TMEM147 Q9BVK8 SYNE4 Homo sapiens Q8N205
Y2H Prey Pooling
25416956
Intra TMEM147 Q9BVK8 CLDN7 Homo sapiens O95471
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CLDN7 Homo sapiens O95471
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 F11R Homo sapiens Q9Y624
Y2H Array
32296183
Intra TMEM147 Q9BVK8 F11R Homo sapiens Q9Y624
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 F11R Homo sapiens Q9Y624
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 KASH5 Homo sapiens Q8N6L0
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 KASH5 Homo sapiens Q8N6L0
Y2H Array
32296183
Intra TMEM147 Q9BVK8 CD79A Homo sapiens P11912
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 CD79A Homo sapiens P11912
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TMEM14B Homo sapiens Q9NUH8
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
Intra TMEM147 Q9BVK8 TMEM14B Homo sapiens Q9NUH8
Y2H Array
32296183
Intra TMEM147 Q9BVK8 TMEM252 Homo sapiens Q8N6L7
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 TMEM252 Homo sapiens Q8N6L7
Y2H Array
32296183
Intra TMEM147 Q9BVK8 HTR2C Homo sapiens P28335
Y2H Prey Pooling
32296183
Intra TMEM147 Q9BVK8 HTR2C Homo sapiens P28335
Y2H Array
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Neurodevelopmental Disorder With Facial Dysmorphism, Absent Language, And Pseudo-Pelger-Huet Anomaly

NEDFLPH
Cystinosis

Cystine Storage Disease

Cystine Diathesis

Cystine Disease

Cystinoses

Protein Defect Of Cystin Transport

Cystin Transport, Protein Defect Of

Nephropathic Cystinosis

Protein Defect Of Cystine Transport
Dirofilariasis

Dirofilaria Infectious Disease

Infection By Dirofilaria
Eosinophilic Meningitis

Eosinophilic Meningoencephalitis Due To Angiostrongylus Cantonensis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14670 TMEM147 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus TMEM147 RGD RGD:1304706
Macaca mulatta TMEM147 VGNC VGNC:79849
Mus musculus TMEM147 MGD MGI:1915011
Bos taurus TMEM147 VGNC VGNC:35978
Felis catus TMEM147 VGNC VGNC:97662
Canis familiaris TMEM147 VGNC VGNC:47480
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