FUNDC2 - FUN14 domain containing 2 Gene

中文名称：含 FUN14 域 2

种属: Homo sapiens

同用名: DC44; HCC3; HCBP6; PD03104

基因 ID: 65991 | 基因类型: protein coding

关于 FUNDC2

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:155,026,844-155,060,304 (from NCBI)

This gene has 7 transcripts (splice variants), 167 orthologues and 1 paralogue. Ubiquitous expression in heart (RPKM 26.0), ovary (RPKM 19.3) and 25 other tissues.

功能概要

预测参与线粒体自噬。位于线粒体中。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in Autophagy of mitochondrion. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

FUNDC2 基因产物(1)

mRNA	Protein	Name
NM_023934.4	NP_076423.2	FUN14 domain-containing protein 2

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables phosphatidylinositol-3,4,5-trisphosphate binding	IDA IDA: 通过直接分析推断	29786068	GOA
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in intracellular triglyceride homeostasis	IMP IMP: 通过突变表型推断	25855506	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

FUNDC2 蛋白结构

FUN14

0
100
189 a.a.

蛋白主名

其他名称

FUN14 domain-containing protein 2

HCC-3

FUNDC2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
Intra	FUNDC2	Q9BWH2	RETREG3	Homo sapiens	Q86VR2	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	RETREG3	Homo sapiens	Q86VR2	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CYB5R3	Homo sapiens	P00387	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CYB5R3	Homo sapiens	P00387	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	ARL13B	Homo sapiens	Q3SXY8	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	ARL13B	Homo sapiens	Q3SXY8	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	KCNJ6	Homo sapiens	P48051	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	KCNJ6	Homo sapiens	P48051	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	STOM	Homo sapiens	P27105	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	STOM	Homo sapiens	P27105	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	FGF14	Homo sapiens	Q92915-2	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	FGF14	Homo sapiens	Q92915-2	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	AQP6	Homo sapiens	Q13520	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	AQP6	Homo sapiens	Q13520	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	TMEM154	Homo sapiens	Q6P9G4	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	TMEM154	Homo sapiens	Q6P9G4	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	GPR152	Homo sapiens	Q8TDT2	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	GPR152	Homo sapiens	Q8TDT2	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CRB3	Homo sapiens	Q9BUF7-2	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CRB3	Homo sapiens	Q9BUF7-2	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	EVI2B	Homo sapiens	P34910-2	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	EVI2B	Homo sapiens	P34910-2	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SLC16A10	Homo sapiens	Q8TF71	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	SLC16A10	Homo sapiens	Q8TF71	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SLC10A6	Homo sapiens	Q3KNW5	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SLC10A6	Homo sapiens	Q3KNW5	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	COX20	Homo sapiens	Q5RI15	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	MFSD14B	Homo sapiens	Q5SR56	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	MFSD14B	Homo sapiens	Q5SR56	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SLC66A2	Homo sapiens	Q8N2U9	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SLC66A2	Homo sapiens	Q8N2U9	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	EBP	Homo sapiens	Q15125	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	EBP	Homo sapiens	Q15125	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SDR16C5	Homo sapiens	Q8N3Y7	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	SDR16C5	Homo sapiens	Q8N3Y7	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	TMX2	Homo sapiens	Q9Y320	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	TMX2	Homo sapiens	Q9Y320	Validated Y2H	32296183
Intra	FUNDC2	Q9BWH2	TMX2	Homo sapiens	Q9Y320	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	CIDEB	Homo sapiens	Q9UHD4	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CIDEB	Homo sapiens	Q9UHD4	Validated Y2H	32296183
Intra	FUNDC2	Q9BWH2	CIDEB	Homo sapiens	Q9UHD4	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	MGST3	Homo sapiens	O14880	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	MGST3	Homo sapiens	O14880	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	REEP4	Homo sapiens	Q9H6H4	Validated Y2H	32296183
Intra	FUNDC2	Q9BWH2	REEP4	Homo sapiens	Q9H6H4	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	REEP4	Homo sapiens	Q9H6H4	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	CD79A	Homo sapiens	P11912	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	CD79A	Homo sapiens	P11912	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SYT2	Homo sapiens	Q8N9I0	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	SYT2	Homo sapiens	Q8N9I0	Y2H Prey Pooling	32296183
Intra	FUNDC2	Q9BWH2	KIR2DL3	Homo sapiens	P43628	Y2H Array	32296183
Intra	FUNDC2	Q9BWH2	KIR2DL3	Homo sapiens	P43628	Y2H Prey Pooling	32296183

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Factor Viii Deficiency

Autosomal Hemophilia A	Hemophilia A
Autosomal Factor Viii Deficiency	Classic Hemophilia A
Congenital Factor Viii Disorder	Subhemophilia
Factor 8 Deficiency, Congenital	Factor Viii

Hemophilia A

Factor Viii Deficiency	Haemophilia A
Mild Hemophilia A	HEMA
Hemophilia, Classic	Classic Hemophilia
Factor 8 Deficiency	Severe Hemophilia A
Classical Hemophilia	Hem A
Hemophilia A, Congenital	Mild Congenital F8 Deficiency
Mild Congenital Factor Viii Deficiency	Severe Congenital F8 Deficiency
Severe Congenital Factor Viii Deficiency	Moderate Hemophilia A
Moderate Congenital F8 Deficiency	Moderate Congenital Factor Viii Deficiency
Bleeding Disorder In Hemophilia A Carriers	Congenital F8 Deficiency
Congenital Fviii Deficiency	Congenital Factor Viii Deficiency
Mild Hereditary Factor Viii Deficiency Disease	Severe Hereditary Factor Viii Deficiency Disease
Ahg - [Antihaemophilic Globulin] Deficiency	Ahg - [Antihaemophilic Globulin] Deficiency Disease
Congenital Factor Viii Disorder	Sex-Linked Factor Viii Deficiency
Antihaemophilic Globulin Deficiency	Classic Haemophilia
Familial Haemophilia	Haemophilia
Hereditary Haemophilia	Subhaemophilia
Haemophilia Nos

X-Linked Intellectual Disability-Cardiomegaly-Congestive Heart Failure Syndrome

Mental Retardation, X-Linked, Syndromic 32

Mrxs32

Non-Syndromic X-Linked Intellectual Disability 72

Mrx72

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To	Hepatitis C Virus Infection, Response To Therapy Of
Hcv	Hcv, Susceptibility To
Hepatitis C Virus, Resistance To	Hepatitis C Virus, Response To Therapy Of
Resistance To Hepatitis C Virus

Syndromic X-Linked Intellectual Disability Shashi Type

Mental Retardation, X-Linked, Syndromic 11, Shashi Type	Mrxs11
Shashi X-Linked Mental Retardation Syndrome	Smrxs
Syndromic X-Linked Intellectual Disability Type 11	X-Linked Mental Retardation Shashi Type
Mental Retardation, X-Linked, Syndromic 11

Moyamoya Disease 1

Moyamoya Disease	Spontaneous Occlusion Of The Circle Of Willis
Mymy	Progressive Intracranial Arterial Occlusion
Moyamoya Syndrome	MYMY1
Cerebrovascular Moyamoya Disease	Moya-Moya Disease
Progressive Intracranial Occlusive Arteropathy	Idiopathic Moyamoya Disease

Non-Syndromic X-Linked Intellectual Disability

X-Linked Non-Syndromic Intellectual Disability	Non-Specific X-Linked Mental Retardation
X-Linked Non-Specific Intellectual Disability

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05146	FUNDC2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Rattus norvegicus	FUNDC2	RGD	RGD:1560916
Bos taurus	FUNDC2	VGNC	VGNC:29144
Mus musculus	FUNDC2	MGD	MGI:1914641
Macaca mulatta	FUNDC2	VGNC	VGNC:81185
Felis catus	FUNDC2	VGNC	VGNC:62389
Canis familiaris	FUNDC2	VGNC	VGNC:41008

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
沪ICP备15051369号-4 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2024 MedChemExpress. All Rights Reserved.

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

FUNDC2 - FUN14 domain containing 2 Gene

关于 FUNDC2

功能概要

FUNDC2 基因产物(1)

FUNDC2 蛋白结构

FUNDC2 蛋白互作信息

关联疾病

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

FUNDC2 - FUN14 domain containing 2 Gene

关于 FUNDC2

功能概要

FUNDC2 基因产物(1)

FUNDC2 蛋白结构

FUNDC2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z