2. Gene
  3. SLC16A10 - solute carrier family 16 member 10 Gene

SLC16A10 - solute carrier family 16 member 10 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 16 成员 10

种属: Homo sapiens

同用名: TAT1; MCT10; PRO0813

基因 ID: 117247 | 基因类型: protein coding

关于 SLC16A10

Cytogenetic location: 6q21 Genomic coordinates (GRCh38): 6:111,087,503-111,231,194 (from NCBI)

This gene has 5 transcripts (splice variants), 247 orthologues and 13 paralogues. Broad expression in placenta (RPKM 4.2), skin (RPKM 2.5) and 19 other tissues.

功能概要

SLC16A10 是质膜氨基酸转运蛋白家族的成员，介导芳香族氨基酸跨质膜的 Na (+) 独立转运。[OMIM 提供，2004 年 4 月]

SLC16A10 is a member of a family of plasma membrane amino acid transporters that mediate the Na(+)-independent transport of aromatic Amino acids across the plasma membrane.[supplied by OMIM, Apr 2004]

SLC16A10 基因产物(1)

mRNA Protein Name
NM_018593.5 NP_061063.2 monocarboxylate transporter 10
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-phenylalanine transmembrane transporter activity IDA
IDA: 通过直接分析推断
11827462 GOA
enables L-tryptophan transmembrane transporter activity IDA
IDA: 通过直接分析推断
11827462 GOA
enables L-tyrosine transmembrane transporter activity IDA
IDA: 通过直接分析推断
11827462 GOA
enables aromatic amino acid transmembrane transporter activity IDA
IDA: 通过直接分析推断
11827462 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables thyroid hormone transmembrane transporter activity IDA
IDA: 通过直接分析推断
18337592 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in aromatic amino acid transport IDA
IDA: 通过直接分析推断
11827462 GOA
involved in thyroid hormone transport IDA
IDA: 通过直接分析推断
18337592 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15918515 GOA
located in plasma membrane IDA
IDA: 通过直接分析推断
18337592 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SLC16A10 蛋白结构

MFS_1

MFS_1: Major Facilitator Superfamily (84 - 378)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 515 a.a.
蛋白主名 其他名称

monocarboxylate transporter 10

MCT 10

SLC16A10 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SLC16A10 Q8TF71 FUNDC2 Homo sapiens Q9BWH2
Validated Y2H
32296183
种属内
SLC16A10 Q8TF71 INSIG2 Homo sapiens Q9Y5U4
Validated Y2H
32296183
种属内
SLC16A10 Q8TF71 TMEM14B Homo sapiens Q9NUH8
Validated Y2H
32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Allan-Herndon-Dudley Syndrome

AHDS

Allan-Herndon Syndrome

Monocarboxylate Transporter 8 Deficiency

MCT8 DEFICIENCY

Mental Retardation, X-Linked, With Hypotonia

Triiodothyronine Resistance

T3 Resistance

Mental Retardation And Muscular Atrophy

Mct8-Specific Thyroid Hormone Cell-Membrane Transporter Deficiency

Intellectual Disability And Muscular Atrophy

Monocarboxylate Transporter-8 Deficiency

T3 Resisitence

Triiodothyronine Resistence

X-Linked Intellectual Disability With Hypotonia

Mct8 -Specific Thyroid Hormone Cell Transporter Deficiency

Monocarboxylate Transporter 8 Deficiency

X-Linked Intellectual Disability-Hypotonia Syndrome
Deafness, Autosomal Recessive 62

DFNB62

Autosomal Recessive Nonsyndromic Deafness 62

Autosomal Recessive Deafness 62
Euthyroid Sick Syndrome

Euthyroid Sick Syndromes

Sick-Euthyroid Syndrome

Ess - [Euthyroid Sick Syndrome]

Low-T3 Syndrome

Ntis - [Non-Thyroidal Illness Syndrome]

Tscitus - [Thyroid Allostasis In Critical Illness, Tumours, Uraemia And Starvation]
Congenital Hypothyroidism

Cretinism

Neonatal Hypothyroidism

Ch

Cht

Congenital Myxedema

Myxedema, Congenital

Endemic Cretinism

Congenital Iodine-Deficiency Syndrome

Fetal Iodine Deficiency Syndrome

Congenital Iodine-Deficiency Hypothyroidism Nos
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13019 SLC16A10 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris SLC16A10 VGNC VGNC:46236
Bos taurus SLC16A10 VGNC VGNC:34684
Rattus norvegicus SLC16A10 RGD RGD:69197
Macaca mulatta SLC16A10 VGNC VGNC:103866
Mus musculus SLC16A10 MGD MGI:1919722
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