2. Gene
  3. CIDEB - cell death inducing DFFA like effector b Gene

CIDEB - cell death inducing DFFA like effector b Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：细胞死亡诱导 DFFA 样效应子 b

种属: Homo sapiens

基因 ID: 27141 | 基因类型: protein coding

关于 CIDEB

Cytogenetic location: 14q12 Genomic coordinates (GRCh38): 14:24,305,187-24,311,435 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele, 192 orthologues and 3 paralogues. Ubiquitous expression in liver (RPKM 36.3), duodenum (RPKM 31.8) and 24 other tissues.

功能概要

实现相同的蛋白质结合活性。参与半胱氨酸型内肽酶活性的激活；细胞死亡的正调节；和从线粒体中释放细胞色素 c 的正调节。作用于凋亡过程的上游或内部。位于细胞质的胞浆和核周区。 [由基因组资源联盟提供，2022 年 4 月]

Enables identical protein binding activity. Involved in activation of cysteine-type endopeptidase activity; positive regulation of cell death; and positive regulation of release of cytochrome c from mitochondria. Acts upstream of or within apoptotic process. Located in cytosol and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CIDEB 基因产物(9)

mRNA Protein Name
NM_001318807.3 NP_001305736.1 cell death activator CIDE-B isoform 1
NM_001393334.1 NP_001380263.1 cell death activator CIDE-B isoform 1
NM_001393335.1 NP_001380264.1 cell death activator CIDE-B isoform 1
NM_001393336.1 NP_001380265.1 cell death activator CIDE-B isoform 1
NM_001393337.1 NP_001380266.1 cell death activator CIDE-B isoform 1
NM_001393338.1 NP_001380267.1 cell death activator CIDE-B isoform 1
NM_001393339.1 NP_001380268.1 cell death activator CIDE-B isoform 1
NM_001393340.1 NP_001380269.1 cell death activator CIDE-B isoform 2
NM_014430.4 NP_055245.2 cell death activator CIDE-B isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12595532 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
12595532 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within apoptotic process IDA
IDA: 通过直接分析推断
12429024 GOA
involved in lipid droplet fusion IMP
IMP: 通过突变表型推断
35939579 GOA
involved in positive regulation of apoptotic process IDA
IDA: 通过直接分析推断
12595532 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytosol IDA
IDA: 通过直接分析推断
12429024 GOA
is active in lipid droplet IDA
IDA: 通过直接分析推断
35939579 GOA
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
12595532 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CIDEB 蛋白结构

CIDE-N

CIDE-N: CIDE-N domain (35 - 110)

  • 0
  • 100
  • 200
  • 219 a.a.
蛋白主名 其他名称

cell death activator CIDE-B

CIDEB 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra CIDEB Q9UHD4 NDRG4 Homo sapiens Q9ULP0-2
Validated Y2H
32296183
Intra CIDEB Q9UHD4 APOC1 Homo sapiens P02654
Y2H Array
32296183
Intra CIDEB Q9UHD4 APOC1 Homo sapiens P02654
Y2H Prey Pooling
32296183
Intra CIDEB Q9UHD4 RHBDD2 Homo sapiens Q6NTF9-3
Y2H Prey Pooling
32296183
Intra CIDEB Q9UHD4 RHBDD2 Homo sapiens Q6NTF9-3
Y2H Array
32296183
Intra CIDEB Q9UHD4 LAMP2 Homo sapiens P13473-2
Y2H Array
32814053
Intra CIDEB Q9UHD4 LAMP2 Homo sapiens P13473-2
Y2H Pooling
32814053
Intra CIDEB Q9UHD4 LAMP2 Homo sapiens P13473-2
Validated Y2H
32814053
Intra CIDEB Q9UHD4 SH3GLB1 Homo sapiens Q9Y371
Y2H Array
32814053
Intra CIDEB Q9UHD4 SH3GLB1 Homo sapiens Q9Y371
Validated Y2H
32814053
Intra CIDEB Q9UHD4 SH3GLB1 Homo sapiens Q9Y371
Y2H Pooling
32814053
Intra CIDEB Q9UHD4 NAALAD2 Homo sapiens Q9Y3Q0
Validated Y2H
32296183
Intra CIDEB Q9UHD4 TAOK2 Homo sapiens Q9UL54
Validated Y2H
32296183
Intra CIDEB Q9UHD4 SAR1B Homo sapiens Q9Y6B6
Validated Y2H
32296183
Intra CIDEB Q9UHD4 MVB12A Homo sapiens Q96EY5
Anti Tag CoIP
33961781
Intra CIDEB Q9UHD4 MVB12A Homo sapiens Q96EY5
Anti Tag CoIP
28514442
Intra CIDEB Q9UHD4 CIDEB Homo sapiens Q9UHD4
Y2H Array
32296183
Intra CIDEB Q9UHD4 CIDEB Homo sapiens Q9UHD4
Y2H
12595532
Intra CIDEB Q9UHD4 CIDEB Homo sapiens Q9UHD4
Pull Down
12595532
Intra CIDEB Q9UHD4 CIDEB Homo sapiens Q9UHD4
Y2H Prey Pooling
32296183
Intra CIDEB Q9UHD4 CIDEB Homo sapiens Q9UHD4
Validated Y2H
32296183
Intra CIDEB Q9UHD4 NFU1 Homo sapiens Q9UMS0
Validated Y2H
32296183
Intra CIDEB Q9UHD4 NME4 Homo sapiens O00746
Y2H Array
32296183
Cross CIDEB Q9UHD4 P27958-PRO_0000037572 Hepatitis C virus P27958-PRO_0000037572
Y2H
12595532
Cross CIDEB Q9UHD4 P27958-PRO_0000037572 Hepatitis C virus P27958-PRO_0000037572
Pull Down
12595532
Cross CIDEB Q9UHD4 P27958-PRO_0000037572 Hepatitis C virus P27958-PRO_0000037572
Confocal
12595532
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS02712 CIDEB Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus CIDEB RGD RGD:1310000
Felis catus CIDEB VGNC VGNC:60901
Bos taurus CIDEB VGNC VGNC:27364
Macaca mulatta CIDEB VGNC VGNC:84324
Mus musculus CIDEB MGD MGI:1270844
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z