MGST2 - microsomal glutathione S-transferase 2 Gene

中文名称：微粒体谷胱甘肽 S-转移酶 2

种属: Homo sapiens

同用名: GST2; MGST-II

关于 MGST2

功能概要

MAPEG (类花生酸和谷胱甘肽代谢中的膜相关蛋白) 家族由六种人类蛋白质组成，其中几种与白三烯和前列腺素 E (炎症的重要介质) 的产生有关。该基因编码一种蛋白质，该蛋白质催化白三烯 A4 和还原型谷胱甘肽结合产生白三烯 C4。已在该基因中鉴定出编码不同亚型的可变剪接转录物变体。[RefSeq 提供，2011 年 2 月]

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2011]