ZP3 蛋白, Human (HEK293, His)

ZP3 protein, a vital component of the zona pellucida, is crucial for sperm binding, inducing the acrosome reaction, and preventing polyspermy. Alongside ZP1, ZP2, and ZP4, it forms a glycoprotein complex in the zona matrix, organizing into filaments cross-linked by ZP1 homodimers. ZP3 actively interacts with ZP1 and ZP2, highlighting its integral role in the molecular architecture governing fertilization processes. ZP3 Protein, Human (HEK293, His) is the recombinant human-derived ZP3 protein, expressed by HEK293 , with N-His, N-Myc labeled tag. The total length of ZP3 Protein, Human (HEK293, His) is 365 a.a., with molecular weight of approximately 55-75 kDa.

作为透明带的重要组成部分，ZP3 蛋白有助于卵母细胞周围的细胞外基质，在介导精子结合、诱导顶体反应和防止受精后多受精方面发挥关键作用。在透明带内，ZP3 与 ZP1、ZP2 和 ZP4 一起形成糖蛋白复合物，对于精子结合和透明带基质的形成至关重要。ZP2 和 ZP3 聚合物组织成由 ZP1 同二聚体交联的长丝，突出了透明带基质的结构复杂性。此外，ZP3 与 ZP1 和 ZP2 积极相互作用，强调了其在控制受精过程的复杂分子结构中不可或缺的作用。

Human

HEK293

N-His;N-Myc

P21754 (23Q-387V)

7784  [NCBI]

QPLWLLQGGASHPETSVQPVLVECQEATLMVMVSKDLFGTGKLIRAADLTLGPEACEPLVSMDTEDVVRFEVGLHECGNSMQVTDDALVYSTFLLHDPRPVGNLSIVRTNRAEIPIECRYPRQGNVSSQAILPTWLPFRTTVFSEEKLTFSLRLMEENWNAEKRSPTFHLGDAAHLQAEIHTGSHVPLRLFVDHCVATPTPDQNASPYHTIVDFHGCLVDGLTDASSAFKVPRPGPDTLQFTVDVFHFANDSRNMIYITCHLKVTLAEQDPDELNKACSFSKPSNSWFPVEGSADICQCCNKGDCGTPSHSRRQPHVMSQWSRSASRNRRHVTEEADVTVGPLIFLDRRGDHEVEQWALPSDTSV

approximately 55-75 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4, 20% Glycerol.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.