2. Epigenetics
  3. MicroRNA
  4. Remlarsen

Remlarsen (MRG-201) 是一种 miR-29b 模拟物，可作为 miR-29b 激动剂。Remlarsen 具有预防纤维化瘢痕或皮肤纤维化形成的潜力。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Remlarsen sodium。

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RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)

Remlarsen Chemical Structure

CAS No. : 1848266-71-6

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规格 价格 是否有货
1 mg ￥1950
询问价格 & 货期
5 mg ￥5450
询问价格 & 货期
10 mg 现货 询问价格 & 货期

* Please select Quantity before adding items.

Remlarsen 的其他形式现货产品:

Customer Review

Other Forms of Remlarsen:

Remlarsen 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Remlarsen (MRG-201), a miR-29b mimic, acts a miR-29b agonist. Remlarsen has the potential for preventiong formation of a fibrotic scar or cutaneous fibrosis[1].

体外研究
(In Vitro)

Remlarsen (MRG-201) is active in regulating PD biomarker expression in the skin[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Remlarsen 相关抗体:
Clinical Trial
分子量

16059.5 (AS: 7961.8; SS: 8097.7)

CAS 号
性状

固体

颜色

White to off-white

Sequence

RNA, (Am-Am-Cm-A-Cm-Um-G-Um-Um-Um-A-Cm-A-A-A-Um-G-G-Um-Cm-Cm-Um-A), 3′-[3-[[6-[(3β)-cholest-5-en-3-yloxy]hexyl]oxy]-2-hydroxypropyl hydrogen phosphate], complex with RNA ((2′-deoxy-2′-fluoro)U-A-G-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)C-(2′-deoxy-2′-fluoro)C-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-G-A-A-A-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)C-A-G-(2′-deoxy-2′-fluoro)U-G-(2′-deoxy-2′-fluoro)U-(2′-deoxy-2′-fluoro)U-sp-U-sp-U) (1:1)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

Remlarsen 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Remlarsen1848266-71-6MRG-201MRG201MRG 201MicroRNAmiRNAmiR-29bmimicfibroticscarcutaneousInhibitorinhibitorinhibit

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目录号：
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