2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor
  3. RAR/RXR
  4. Retinoic acid

Retinoic acid  (Synonyms: 维生素A酸; Vitamin A acid; all-trans-Retinoic acid; ATRA)

目录号: HY-14649G
产品使用指南

摩尔计算器

Retinoic acid (Vitamin A acid) (GMP) 是 GMP 级别的 Retinoic acid (HY-14649)。GMP 级别的小分子可用做细胞疗法中的辅助试剂。Retinoic acid 是 RAR 核受体的激动剂。

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Retinoic acid Chemical Structure

Retinoic acid Chemical Structure

CAS No. : 302-79-4

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规格 价格 是否有货 数量
10 mg ￥10800
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Other Forms of Retinoic acid:

Retinoic acid 相关抗体

Top Publications Citing Use of Products

查看 RAR/RXR 亚型特异性产品:

查看所有亚型
RXRα RXRβ RXRγ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Retinoic acid (Vitamin A acid) (GMP) is Retinoic acid (HY-14649) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Retinoic acid is an agonist of RAR nuclear receptors[1][2][3][4][5][6].

体外研究
(In Vitro)

Retinoic acid (GMP) time- and dose- dependently induces differentiation of EC cells and ES cells into specific cell types[1].
Retinoic acid (GMP) induces partial differentiation of F9 embryonal carcinoma cells into endoderm cells[2].
Retinoic acid (GMP) (100 nM; 2-8 d) promotes photoreceptor differentiation in early postnatal retinal cultures[3].
Retinoic acid (GMP) (0.1 μM; 10-12 d) induces human SH-SY5Y neuroblastoma cells differentiation with long cell processes[4].
Retinoic acid (GMP) (0-10 μM; 48 h) dose-dependently induces morphologic differentiation of LA-N-1 human neuroblastoma cells[5].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Retinoic acid 相关抗体:
体内研究
(In Vivo)

Retinoic acid (GMP) (0.3 μM; embryos are immersed in tank water containing retinoic acid) accelerates of rod differentiation is observed following 24 and 48 hours of application in zebrafish[6].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
分子量

300.44

Formula

C20H28O2
CAS 号
性状

固体

颜色

Light brown to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 50 mg/mL (166.42 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.3285 mL 16.6423 mL 33.2845 mL
5 mM 0.6657 mL 3.3285 mL 6.6569 mL
查看完整储备液配制表

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Retinoic acid 相关分类

完整储备液配制表

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3285 mL 16.6423 mL 33.2845 mL 83.2113 mL
5 mM 0.6657 mL 3.3285 mL 6.6569 mL 16.6423 mL
10 mM 0.3328 mL 1.6642 mL 3.3285 mL 8.3211 mL
15 mM 0.2219 mL 1.1095 mL 2.2190 mL 5.5474 mL
20 mM 0.1664 mL 0.8321 mL 1.6642 mL 4.1606 mL
25 mM 0.1331 mL 0.6657 mL 1.3314 mL 3.3285 mL
30 mM 0.1109 mL 0.5547 mL 1.1095 mL 2.7737 mL
40 mM 0.0832 mL 0.4161 mL 0.8321 mL 2.0803 mL
50 mM 0.0666 mL 0.3328 mL 0.6657 mL 1.6642 mL
60 mM 0.0555 mL 0.2774 mL 0.5547 mL 1.3869 mL
80 mM 0.0416 mL 0.2080 mL 0.4161 mL 1.0401 mL
100 mM 0.0333 mL 0.1664 mL 0.3328 mL 0.8321 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Retinoic acid (GMP)302-79-4Vitamin A acid (GMP) all-trans-Retinoic acid (GMP) ATRA (GMP)RAR/RXRRetinoic acid receptorsRetinoid X receptorsGMPdifferentiationECESF9 embryonal carcinoma cellSH-SY5Y neuroblastomaneuroblastomaInhibitorinhibitorinhibit

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