2. Neuronal Signaling
  3. Amyloid-β
  4. RI-OR2

RI-OR2 是一种逆转录肽，是一种淀粉样蛋白-β (Aβ) 寡聚化抑制剂。RI-OR2 与固定的 β-Amyloid (1-42) (HY-P1363A) 单体和原纤维结合，表观 Kd 为 9-12 μM，也可作为 Aβ(1-42) 原纤维延伸的抑制剂。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Custom Peptide Synthesis

RI-OR2 Chemical Structure

RI-OR2 Chemical Structure

CAS No. : 1219627-58-3

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RI-OR2 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RI-OR2, a retro-inverso peptide, is an amyloid-β (Aβ) oligomerization inhibitor. RI-OR2 binds to immobilized β-Amyloid (1-42) (HY-P1363A) monomers and fibrils, with an apparent Kd of 9-12 μM, and also acted as an inhibitor of Aβ(1-42) fibril extension[1].

体外研究
(In Vitro)

RI-OR2 可显著逆转 Aβ(1-42) 对培养的 SH-SY5Y 神经母细胞瘤细胞的毒性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

RI-OR2 相关抗体:
分子量

1120.35

Formula

C53H85N17O10
CAS 号
Sequence

Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-NH2
Sequence Shortening

Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RI-OR2 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RI-OR21219627-58-3Amyloid-ββ-amyloid peptideAβAbetaretro-inverso peptideamyloid-β oligomerization inhibitor,Inhibitorinhibitorinhibit

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目录号：
HY-P10823
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