2. GPCR/G Protein Neuronal Signaling
  3. mGluR
  4. (RS)-PPG

(RS)-PPG 是一种有效的，选择性 III 型 mGluR 激动剂。对 hmGluR4a，hmGluR6，hmGluR7b 和 hmGluR8a 的 EC50 分别为 5.2 μM，4.7 μM，185 μM 和 0.2 μM，具有抗惊厥和神经保护活性。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

(RS)-PPG Chemical Structure

(RS)-PPG Chemical Structure

CAS No. : 120667-15-4

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
1 mg ￥1150
In-stock
5 mg   询价  
10 mg   询价  

* Please select Quantity before adding items.

Customer Review

(RS)-PPG 相关抗体

Top Publications Citing Use of Products

查看 mGluR 亚型特异性产品:

查看所有亚型
mGluR1 mGluR2 mGluR3 mGluR4 mGluR5 mGluR6 mGluR7 mGluR8 mGluR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(RS)-PPG is a potent and selective agonist for group III mGluRs. The EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective activity[1].

IC50 & Target[1]

hmGluR4a

5.2 μM (EC50)

hmGluR6

4.7 μM (EC50)

hmGluR7b

185 μM (EC50)

hmGluR8a

0.2 μM (EC50)

体外研究
(In Vitro)

Activation of group III mGluRs by treatment of neurons with (R,S)-PPG (100 μM) can significantly suppress the elevation of intracellular calcium and protect neurons from apoptosis induced by Aβ[31-35] (25 μM)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(RS)-PPG 相关抗体:
分子量

231.14

Formula

C8H10NO5P
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

COA (169 KB)

产品使用指南 (1538 KB)
参考文献

(RS)-PPG 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(RS)-PPG120667-15-4mGluRMetabotropic glutamate receptorshmGluR4ahmGluR6hmGluR7bhmGluR8aAnticonvulsiveneuroprotectiveInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
(RS)-PPG
目录号：
HY-107514
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z