1. 多肽产品
  2. 多肽及其衍生物
  3. 多肽药物递送
  4. 细胞穿膜肽
  5. (RXR)4XB

(RXR)4XB 是一种细胞穿透肽,可结合磷二酰胺吗啉寡聚体 (PMO),形成肽结合的 PMO (PPMO),并改善 PMO 向细菌细胞中的输送。(RXR)4XB-PMO 偶合物可防止生物膜的形成,抑制 Pseudomonas aeruginosa (MIC50 为 0.5-16 μM),并降低小鼠急性肺炎模型中的细菌负荷。

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Custom Peptide Synthesis

(RXR)4XB Chemical Structure

(RXR)4XB Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(RXR)4XB is a cell-penetrating peptide, that binds the phosphorodiamidate morpholino oligomers (PMOs), forms peptide-conjugated PMOs (PPMOs), and improves the delivery of PMO into bacterial cells. (RXR)4XB-PMO conjugate prevents the formation of biofilms, inhibits Pseudomonas aeruginosa with MIC50 of 0.5 to 16 μM, and reduces the bacterial burden in mouse acute pneumonia models[1].

分子量

1903.38

Formula

C81H159N39O14

Sequence

Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-Arg-{Ahx}-Arg-{Ahx-βAla}-NH2

Sequence Shortening

R-{Ahx}-RR-{Ahx}-RR-{Ahx}-RR-{Ahx}-R-{Ahx-βAla}-NH2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Inquiry Information

产品名称:
(RXR)4XB
目录号:
HY-P10559
需求量: