1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. SB251023

SB251023 是一种 β3-肾上腺素能受体 (β3-adrenergic receptor) 激动剂,对 β3a-β3b 肾上腺素能受体的 pEC50 分别为 7.14 和 6.91。SB251023 能够调节细胞的环状 AMP 水平和细胞外酸化速率 (EAR)。SB251023 在心血管疾病和代谢相关疾病的研究中具有潜在应用价值。

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SB251023 Chemical Structure

SB251023 Chemical Structure

CAS No. : 208842-53-9

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生物活性

SB251023 is a β3-adrenergic receptor agonist with pEC50 values of 7.14 and 6.91 for the β3a- and β3b-adrenergic receptors, respectively. SB251023 is capable of modulating cyclic AMP levels and extracellular acidification rate (EAR) in cells. It has potential application value in the study of cardiovascular diseases and metabolic-related disorders[1].

IC50 & Target

Beta-3 adrenergic receptor

 

分子量

511.55

Formula

C28H34NO6P

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SB251023
目录号:
HY-119497
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