2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. SCH-23390

SCH-23390  (Synonyms: R-(+)-SCH-23390)

目录号: HY-19545
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SCH-23390 是一种多巴胺 D1 样受体拮抗剂 (D1 和 D5 受体亚型的 Ki 值分别为 0.2 nM 和 0.3 nM)。SCH-23390 可缩短可卡因诱导的大鼠杠杆按压行为的潜伏期。SCH-23390 还可以消除由化学惊厥剂毛果芸香碱 (HY-B0726A) 和梭曼引发的全身性癫痫发作，用于多巴胺系统的神经疾病研究。

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SCH-23390 Chemical Structure

SCH-23390 Chemical Structure

CAS No. : 87075-17-0

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SCH-23390 的其他形式现货产品:

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SCH-23390 相关抗体

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

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  • 参考文献

生物活性

SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively). SCH-23390 can shorten the latency period for cocaine-induced lever pressing behavior in rats. SCH-23390 can also eliminate generalized seizures caused by chemical convulsants, such as arecoline (HY-B0726A) and strychnine, and is used in research on neurological disorders related to the dopamine system[1][2].

分子量

287.78

Formula

C17H18ClNO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SCH-23390 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SCH-2339087075-17-0R-(+)-SCH-23390SCH23390SCH 23390Dopamine Receptorcocaineratlever pressing behaviorInhibitorinhibitorinhibit

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