Secretin (28-54), human TFA  (Synonyms: Human secretin TFA)

Secretin (28-54), human TFA is a 27-amino acid residue C-terminally amidated peptide, which acts on human secretin receptors^[1].

Secretin is a hormone produced and secreted from the endocrine S cells in response to the gastric acid and lipid components. Secretin potentiates enzyme secretion from the acinar cell. Secretin is also a putative mitogen to promote pancreatic growth. In the stomach and gall bladder, Secretin inhibits gastric emptying and acid release and stimulates biliary output of water and bicarbonate. Secretin elicits its biological effects by interacting with specific cell surface receptors^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3039.46 (free base)

C₁₃₀H₂₂₀N₄₄O₄₀.xC₂HF₃O₂

固体

White to off-white

His-Ser-Asp-Gly-Thr-Phe-Thr-Ser-Glu-Leu-Ser-Arg-Leu-Arg-Glu-Gly-Ala-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Gly-Leu-Val-NH2

HSDGTFTSELSRLREGARLQRLLQGLV-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

• [1]. Pang RT, et al. Role of N-linked glycosylation on the function and expression of the human secretin receptor. Endocrinology. 1999 Nov;140(11):5102-11.  [Content Brief]