1. GPCR/G Protein Others
  2. LPL Receptor Isotope-Labeled Compounds
  3. Siponimod-d11

Siponimod-d11  (Synonyms: BAF-312-d11)

目录号: HY-12355S
产品使用指南

Siponimod-d11 是 Siponimod (HY-12355) 的氘代物。Siponimod 是一种口服有效、选择性的鞘脂 S1P 受体调节剂。Siponimod 对 S1P1S1P5 受体的选择性高于 S1P2S1P3S1P4EC50 分别为 0.39,0.98,>10000,>1000 和 750 nM。Siponimod 可用于多发性硬化症 (MS) 的研究。

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Siponimod-d<sub>11</sub> Chemical Structure

Siponimod-d11 Chemical Structure

CAS No. : 2104759-32-0

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规格 是否有货
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Other Forms of Siponimod-d11:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Siponimod-d11 is deuterium labeled Siponimod (HY-12355). Siponimod is an orally active and selective sphingosine-1-phosphate (S1P) receptor modulator. Siponimod is selective for S1P1 and S1P5 over S1P2, S1P3, and S1P4, with EC50s of 0.4, 0.98, >10000, >1000, and 750 nM, respectively. Siponimod can be used for multiple sclerosis (MS) research[1][2][3][4].

分子量

527.66

Formula

C29H24D11F3N2O3

CAS 号
非标记 CAS

1230487-00-9

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
HY-12355S
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