2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Solabegron hydrochloride

Solabegron hydrochloride  (Synonyms: GW 427353B)

目录号: HY-19436A
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摩尔计算器

Solabegron hydrochloride 是 β3 肾上腺素能受体 (β3-AR) 的选择性激动剂, 在中国仓鼠卵巢细胞中测得的 EC50 值为22 nM。可用于膀胱过度活跃和肠易激综合征的研究。

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Solabegron hydrochloride Chemical Structure

Solabegron hydrochloride Chemical Structure

CAS No. : 451470-34-1

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Solabegron hydrochloride 的其他形式现货产品:

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Solabegron hydrochloride 相关抗体

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Solabegron hydrochloride is a selective β3-adrenergic receptor agonist, stimulating cAMP accumulation in Chinese hamster ovary cells expressing the human β3-AR, with an EC50 value of 22 nM[1]. Solabegron hydrochloride (GW 427353) is being developed for the treatment of overactive bladder and irritable bowel syndrome[1].

分子量

447.35

Formula

C23H24Cl2N2O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Solabegron hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Solabegron451470-34-1GW 427353BAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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