2. Immunology/Inflammation
  3. STING
  4. STING agonist-7

STING agonist-7 是一种非核苷酸 STING 激动剂，选择性结合小鼠 STING 而不是人类 STING。STING agonist-7 穿透细胞膜较差。

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STING agonist-7 Chemical Structure

STING agonist-7 Chemical Structure

CAS No. : 2767442-46-4

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥2220
In-stock
1 mg ￥1363
In-stock
5 mg ￥3000
In-stock
10 mg ￥4800
In-stock
25 mg 现货 询价
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

STING agonist-7 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

STING agonist-7 is a non-nucleotide STING agonist. STING agonist-7 binds selectively to mouse STING but not human STING. STING agonist-7 penetrates cell membrane poorly[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H69AR EC50
> 100 μM
Compound: 11
Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1 Dual cells assessed as IRF reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
[PMID: 35108011]
H69AR EC50
> 100 μM
Compound: 11
Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
Agonist activity at STING in human THP1-Dual cells assessed as NF-kappaB reporter activation incubated for 20 hrs by quanti-blue SEAP reporter gene assay
[PMID: 35108011]
体外研究
(In Vitro)

STING agonist-7 (compound 11) is active in biochemical assays but inactive in cellular reporter assays[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

STING agonist-7 相关抗体:
分子量

336.30

Formula

C17H12N4O4
CAS 号
性状

固体

颜色

Light brown to brown

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 62.5 mg/mL (185.85 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.9735 mL 14.8677 mL 29.7354 mL
5 mM 0.5947 mL 2.9735 mL 5.9471 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

STING agonist-7 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9735 mL 14.8677 mL 29.7354 mL 74.3384 mL
5 mM 0.5947 mL 2.9735 mL 5.9471 mL 14.8677 mL
10 mM 0.2974 mL 1.4868 mL 2.9735 mL 7.4338 mL
15 mM 0.1982 mL 0.9912 mL 1.9824 mL 4.9559 mL
20 mM 0.1487 mL 0.7434 mL 1.4868 mL 3.7169 mL
25 mM 0.1189 mL 0.5947 mL 1.1894 mL 2.9735 mL
30 mM 0.0991 mL 0.4956 mL 0.9912 mL 2.4779 mL
40 mM 0.0743 mL 0.3717 mL 0.7434 mL 1.8585 mL
50 mM 0.0595 mL 0.2974 mL 0.5947 mL 1.4868 mL
60 mM 0.0496 mL 0.2478 mL 0.4956 mL 1.2390 mL
80 mM 0.0372 mL 0.1858 mL 0.3717 mL 0.9292 mL
100 mM 0.0297 mL 0.1487 mL 0.2974 mL 0.7434 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STING agonist-72767442-46-4STING agonist7STING agonist 7STINGStimulator of Interferon GenesTMEM173MITAERISMPYSSTING agonistpenetrates cell membrane poorlyInhibitorinhibitorinhibit

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产品名称：
STING agonist-7
目录号：
HY-143896
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