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SU9518是一种酪氨酸激酶抑制剂,具有针对PDGFRα的特异活性。SU9518可以抑制纤维母细胞和穆勒细胞兔模型中增殖性玻璃体视网膜病(PVR)的发展。SU9518在这些模型中表现出有效的抑制作用,且无毒性影响。因此,SU9518有潜力被用于抑制人类的PVR及其他涉及纤维化和胶质增生的增殖性眼病。

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SU9518 Chemical Structure

SU9518 Chemical Structure

CAS No. : 251356-32-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SU9518 is a tyrosine kinase inhibitor with specific activity against PDGFRα. SU9518 can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Muller cell rabbit models. SU9518 showed effective inhibitory effects in these models without toxic effects. Therefore, SU9518 has the potential to be used to inhibit PVR in humans and other proliferative eye diseases involving fibrosis and gliosis[1].

分子量

389.24

Formula

C18H17BrN2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SU9518 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SU9518
目录号:
HY-112352
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