2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel Sodium Channel
  4. Sulcardine

Sulcardine 是一种多离子通道阻滞剂，可以降低 INa 和 ICa，IC50 分别 26.9 µM 和 69.2 µM。Sulcardine 是一种有效的 hNav1.5 通道 阻滞剂，同时对 hERG 通道有轻微的抑制作用。Sulcardine 具有抗心律失常的作用。

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Sulcardine Chemical Structure

Sulcardine Chemical Structure

CAS No. : 343935-60-4

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Other Forms of Sulcardine:

Sulcardine 相关抗体

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N-type calcium channel L-type calcium channel P/Q-type calcium channel T-type calcium channel Calcium Channel

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulcardine is a multi-ion channel blocker that can reduce INa and ICa with IC50 values of 26.9 µM and 69.2 µM, respectively. Sulcardine is a potent hNav1.5 channel blocker with a mild inhibitory effect on hERG channels. Sulcardine has anti-arrhythmic effects[1][2].

IC50 & Target

IC50: 26.9 µM (INa)[1].
IC50: 69.2 µM (ICa)[1].
分子量

459.60

Formula

C24H33N3O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sulcardine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Sulcardine343935-60-4Calcium ChannelSodium ChannelCa2+ channelsCa channelsNa channelsNa+ channelsArrhythmiasSodium channelCalcium channelInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-156976
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