1. Anti-infection NF-κB Autophagy Apoptosis Others
  2. Antibiotic Autophagy NF-κB Bacterial Ferroptosis Apoptosis Isotope-Labeled Compounds
  3. Sulfasalazine-d3,15N

Sulfasalazine-d3,15N  (Synonyms: 柳氮磺吡啶-d3; NSC 667219-d3,15N)

目录号: HY-14655S1
产品使用指南

Sulfasalazine-d3,15N 是 15N 和氘代标记的 Sulfasalazine (HY-14655)。Sulfasalazine (NSC 667219) 常用于类风湿关节炎和溃疡性结肠炎的相关研究。Sulfasalazine 可抑制 NF-κB 的活性。Sulfasalazine 是 type 1 的铁死亡 (ferroptosis) 诱导剂。

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Sulfasalazine-d<sub>3</sub>,<sup>15</sup>N Chemical Structure

Sulfasalazine-d3,15N Chemical Structure

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     可免费申领三个不同产品的试用装。

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规格 是否有货
1 mg 询价

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Other Forms of Sulfasalazine-d3,15N:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sulfasalazine-d3,15N is 15N and deuterated labeled Sulfasalazine (HY-14655). Sulfasalazine (NSC 667219) is an anti-rheumatic agent for the research of rheumatoid arthritis and ulcerative colitis. Sulfasalazine can suppress NF-κB activity. Sulfasalazine is a type 1 ferroptosis inducer[1][2][3][4].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

At low doses (0.25 mM), SAS is able to suppress glioma growth by over 60% compared to untreated controls[4].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

402.40

Formula

C18H11D3N315NO5S

非标记 CAS

599-79-1

中文名称

柳氮磺吡啶-d3;水扬酸偶氮磺胺毗咙-d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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目录号:
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