1. GPCR/G Protein Neuronal Signaling
  2. Adrenergic Receptor
  3. Tilisolol hydrochloride

Tilisolol hydrochloride  (Synonyms: N-696)

目录号: HY-122215
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Tilisolol hydrochloride (N-696) 是一种非选择性的β-肾上腺素能拮抗剂,具有血管扩张和降压活性。Tilisolol hydrochloride 通过打开ATP敏感的K+通道在犬的冠状动脉中发挥作用。Tilisolol hydrochloride 在KCl预收缩的大鼠胸主动脉中显示出浓度相关的放松作用。Tilisolol hydrochloride 在脊髓刺激的大鼠中以剂量依赖的方式降低舒张血压,并轻微增加心率。

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Tilisolol hydrochloride Chemical Structure

Tilisolol hydrochloride Chemical Structure

CAS No. : 62774-96-3

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生物活性

Tilisolol hydrochloride (N-696) is a non-selective β-adrenergic antagonist with vasodilatory and hypotensive activities. Tilisolol hydrochloride exerts its effects in canine coronary arteries by opening ATP-sensitive K+ channels. Tilisolol hydrochloride exhibits concentration-dependent relaxation in KCl-precontracted rat thoracic aorta. Tilisolol hydrochloride reduces diastolic blood pressure in a dose-dependent manner and slightly increases heart rate in spinal cord stimulated rats[1].

分子量

340.85

Formula

C17H25ClN2O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tilisolol hydrochloride
目录号:
HY-122215
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