2. Apoptosis
  3. TNF Receptor
  4. Toralizumab

Toralizumab  (Synonyms: 托拉珠单抗; IDEC-131; Anti-Human CD40 ligand Recombinant Antibody)

目录号: HY-P99325 纯度: 99.57%
COA

摩尔计算器

Toralizumab (IDEC-131) 是一种针对 CD40L (CD154) 的人源化单克隆抗体 (mAb)，由人 γ1 重链和人 kappa 轻链组成。Toralizumab 特异性结合 T 细胞上的人 CD40L，从而阻止 CD40 信号传导。Toralizumab 是一种免疫抑制剂，具有用于活跃的系统性红斑狼疮 (SLE) 研究的潜力。

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CAS No. : 252662-47-8

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规格 价格 是否有货 数量
1 mg ￥3500
In-stock
5 mg ￥9100
In-stock
10 mg   询价  
50 mg   询价  

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Toralizumab 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

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TNFRSF1A/CD120a TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab, a immunosuppressive agent, has the potential for active systemic lupus erythematosus (SLE) research[1][2].

IC50 & Target[1][2]

CD40L

 

CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

托拉珠单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG1 kappa
纯度 & 产品资料
参考文献

Toralizumab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Toralizumab252662-47-8IDEC-131 Anti-Human CD40 ligand Recombinant Antibody托拉珠单抗IDEC131IDEC 131TNF ReceptorTumor Necrosis Factor ReceptorTNFRHumanizedmonoclonal antibodymAbCD40LCD154gamma 1 heavy chainskappa light chainsT cellssystemic lupus erythematosusSLEInhibitorinhibitorinhibit

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