2. Others JAK/STAT Signaling Immunology/Inflammation Neuronal Signaling Stem Cell/Wnt Epigenetics GPCR/G Protein Membrane Transporter/Ion Channel Protein Tyrosine Kinase/RTK NF-κB MAPK/ERK Pathway
  3. JAK nAChR 5-HT Receptor NF-κB p38 MAPK Nuclear Factor of activated T Cells (NFAT) Isotope-Labeled Compounds AP-1
  4. Tropisetron-d5

Tropisetron-d5  (Synonyms: 托烷司琼-d5; SDZ-ICS-930-d5 free base)

目录号: HY-B0072S
产品使用指南

摩尔计算器

Tropisetron-d5 (SDZ-ICS-930-d5 (free base)) 是氘代标记的 Tropisetron。Tropisetron (SDZ-ICS-930 free base) 是口服有效的抗炎剂和止吐剂。Tropisetron 是 5-HT3R 拮抗剂，Ki 为 5.3 nM。Tropisetron 也是 α7 烟碱受体 (α7 nAChR) 部分激动剂，EC50 为 1.3 μM。此外，Tropisetron 具有抗肿瘤的和神经保护的作用。

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Tropisetron-d<sub>5</sub> Chemical Structure

Tropisetron-d5 Chemical Structure

CAS No. : 1220284-86-5

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Other Forms of Tropisetron-d5:

Tropisetron-d5 相关抗体

Top Publications Citing Use of Products

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JAK1 JAK2 JAK3 Tyk2 JAK

查看 5-HT Receptor 亚型特异性产品:

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tropisetron-d5 (SDZ-ICS-930-d5 (free base)) is deuterium labeled Tropisetron. Tropisetron (SDZ-ICS-930 free base) is an orally active anti-inflammatory and antiemetic agent. Tropisetron is 5-HT3R antagonists with a Ki of 5.3 nM. Tropisetron is also a partial agonist of α7 nicotinic receptor (α7 nAChR) with an EC50 of 1.3 μM. In addition, Tropisetron has antitumor and neuroprotective effects[1][2][3][4][5][6][7].

分子量

289.38

Formula

C17H15D5N2O2
CAS 号
非标记 CAS

89565-68-4
中文名称

托烷司琼-d5
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tropisetron-d5 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tropisetron-d51220284-86-5SDZ-ICS-930-d5托烷司琼-d5JAKnAChR5-HT ReceptorNF-κBp38 MAPKNuclear Factor of activated T Cells (NFAT)Isotope-Labeled CompoundsAP-1Janus kinaseNicotinic acetylcholine receptorsSerotonin Receptor5-hydroxytryptamine ReceptorNuclear factor-κBNuclear factor-kappaBActivator Protein 1Inhibitorinhibitorinhibit

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