1. Anti-infection
  2. Bacterial
  3. Tuberculosis inhibitor 1

Tuberculosis inhibitor 1 是一种有效且无细胞毒性的 trypanosoma brucei 生长抑制剂,EC50 值为 5 nM.

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Tuberculosis inhibitor 1 Chemical Structure

Tuberculosis inhibitor 1 Chemical Structure

CAS No. : 2230810-28-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tuberculosis inhibitor 1 is a potent and non-cytotoxic trypanosoma brucei growth inhibitor with an EC50 of 5 nM[1].

IC50 & Target

EC50: 5 nM (Trypanosoma brucei)[1]

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HeLa CC50
> 25000 nM
Compound: 34, Epimeric mixture
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by celltiter glo assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by celltiter glo assay
[PMID: 30482621]
体外研究
(In Vitro)

Tuberculosis inhibitor 1 is selective over other parasites, such as Trypanosoma cruzi and Plasmodium falciparum (T. cruzi EC50 8120 nM, P. falciparum EC50 3624 nM)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

563.69

Formula

C34H37N5O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Tuberculosis inhibitor 1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tuberculosis inhibitor 1
目录号:
HY-119938
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