1. Inhibitory Antibodies
  2. Tusamitamab

Tusamitamab  (Synonyms: 特赛妥单抗)

目录号: HY-P99054 纯度: 99.75%
COA

Tusamitamab 是一种靶向 CEACAM5IgG1 单克隆抗体。Tusamitamab 可用于合成 Tusamitamab ravtansine (SAR408701),Tusamitamab ravtansine 是首创的人源化抗体活性分子偶联物 (ADC),结合了 Tusamitamab 和 DM4 (一种强效美登素衍生物)。

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CAS No. : 2349294-95-5

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规格 价格 是否有货 数量
1 mg ¥2000
In-stock
5 mg ¥6000
In-stock
10 mg ¥9600
In-stock
50 mg   询价  
100 mg   询价  

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize Tusamitamab ravtansine (SAR408701), which is a first-in-class humanized antibody-drug conjugate (ADC) that combines Tusamitamab and DM4 (a potent maytansine derivative)[1].

同型

Human IgG1 kappa

推荐同型对照抗体
种属

Chimeric

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

特赛妥单抗

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG1 kappa
Biological Activity
  • Loaded CEACAM5 Protein, Human (HEK293, His, solution, HY-P75356) on AHC2 biosensor, can bind Tusamitamab with an affinity constant of 6.031E-09 M as determined in BLI assay.
  • Immobilized CEACAM5 Protein, Human can bind Tusamitamab. The EC50 for this effect is 4.02 ng/mL.
纯度 & 产品资料

纯度: 99.75%

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Tusamitamab
目录号:
HY-P99054
需求量: