2. GPCR/G Protein
  3. CRFR
  4. [Tyr0] Corticotropin Releasing Factor, ovine

[Tyr0] Corticotropin Releasing Factor, ovine 

目录号: HY-P3687
产品使用指南

摩尔计算器

[Tyr0] Corticotropin Releasing Factor, ovine 是一种从绵羊中分离出来的促肾上腺皮质激素释放因子/激素。促肾上腺皮质激素释放因子 (CRF) 是一种下丘脑激素，刺激促肾上腺皮质激素 (ACTH) 和 β-内啡肽的释放。

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Custom Peptide Synthesis

[Tyr0] Corticotropin Releasing Factor, ovine Chemical Structure

[Tyr0] Corticotropin Releasing Factor, ovine Chemical Structure

CAS No. : 83930-34-1

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[Tyr0] Corticotropin Releasing Factor, ovine 相关抗体

Top Publications Citing Use of Products

查看 CRFR 亚型特异性产品:

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CRFR1 CRFR2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

[Tyr0] Corticotropin Releasing Factor, ovine is a corticotropin releasing factor/hormone isolated from ovine. Corticotropin releasing factor (CRF) is a hypothalamic hormone, stimulates the release of adrenocorticotropic hormone (ACTH) and of β-endorphin[1][2].

体外研究
(In Vitro)

[Tyr0] Corticotropin Releasing Factor, ovine has a strong binding effect with plasma protein[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

[Tyr0] Corticotropin Releasing Factor, ovine 相关抗体:
体内研究
(In Vivo)

[Tyr0] Corticotropin Releasing Factor, ovine (328 μCi/μg; 198 pg/min or 225 pg/min; continuous infusions intravenous; single dose lasting 5-7 hr) shows a long plasma half-life and low metabolic clearance rate in male cynomolgus monkeys[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Young adult male cynomolgus monkeys (4.0-6.9 kg)[1]
Dosage: 10 mL/h for 198 pg/min or 225 pg/min
Administration: Continuous infusions intravenous; collected every 60 min during 5-7 hr
Result: Showed a longer plasma half-life than for all other known hypothalamic peptides and its metabolic clearance rate was relatively low and considerably less all other known hypothalamic peptides or adreno-cortico-tropic-hormone (ACTH).
分子量

4833.48

Formula

C214H348N60O65S
CAS 号
Sequence Shortening

Tyr-Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

[Tyr0] Corticotropin Releasing Factor, ovine 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Tyr0] Corticotropin Releasing Factor, ovine83930-34-1CRFRCorticotropin-releasing Factor ReceptorCRHRhypothalamic hormoneadrenocorticotrophic hormoneACTHCRFCRHInhibitorinhibitorinhibit

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