2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Vatinoxan

Vatinoxan  (Synonyms: MK-467; L-659066)

目录号: HY-19057
产品使用指南

摩尔计算器

Vatinoxan (MK-467) 是一种 α2-肾上腺素受体 (alpha 2-adrenergic receptor) 拮抗剂。Vatinoxan 的外周选择性决定它在血脑屏障的穿透性有限，因此在中枢神经系统中的浓度较低。Vatinoxan 通过与 α2-肾上腺素受体 (alpha 2-adrenergic receptor) 结合来拮抗这些受体，从而减少或防止由 α2-肾上腺素受体激动剂引起的心血管效应。Vatinoxan 可用于心血管效应，镇静和镇痛的研究。

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Vatinoxan Chemical Structure

Vatinoxan Chemical Structure

CAS No. : 114914-42-0

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Vatinoxan 的其他形式现货产品:

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Vatinoxan 相关抗体

Top Publications Citing Use of Products

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Vatinoxan (MK-467) is an alpha 2-adrenergic receptor antagonist. The peripheral selectivity of Vatinoxan determines that it has limited penetration across the blood-brain barrier and therefore has low concentrations in the central nervous system. Vatinoxan antagonizes alpha 2-adrenergic receptor receptors by binding to them, thereby reducing or preventing cardiovascular effects caused by α2-adrenergic agonists. Vatinoxan can be used in studies of cardiovascular effects, sedation and analgesia[1].

分子量

418.51

Formula

C20H26N4O4S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Vatinoxan 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vatinoxan114914-42-0MK-467 L-659066MK467MK 467L659066L 659066L-659066Adrenergic ReceptorBeta ReceptorAntagonistperipheral selectivitycardiovascular effectssedationanalgesiaInhibitorinhibitorinhibit

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