2. Anti-infection
  3. Parasite
  4. Vinclozolin M2

Vinclozolin M2 是 Vinclozolin 的活性代谢物。它由 Vinclozolin 通过连续酯酶活性和秀丽隐杆线虫中的 Vinclozolin 脱羧以及人类肝微粒体中的脱羧而形成。在使用 MCF-7 细胞的报告测定中，Vinclozolin M2 是盐皮质激素受体（IC50=1,400 nM）和雄激素受体（IC50=0.17 nM）的拮抗剂。

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Vinclozolin M2 Chemical Structure

Vinclozolin M2 Chemical Structure

CAS No. : 83792-61-4

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Vinclozolin M2 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Vinclozolin M2 is an active metabolite of vinclozolin. It is formed from vinclozolin by successive esterase activity and decarboxylation of vinclozolin in C. elegans and by decarboxylation in human liver microsomes. Vinclozolin M2 is an antagonist of the mineralocorticoid receptor (IC50=1,400 nM) and androgen receptor (IC50=0.17 nM) in reporter assays using MCF-7 cells.

分子量

260.12

Formula

C11H11Cl2NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Vinclozolin M2 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vinclozolin M283792-61-4Vinclozolin M 2Vinclozolin M-2ParasiteInhibitorinhibitorinhibit

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目录号：
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