2. Metabolic Enzyme/Protease Vitamin D Related/Nuclear Receptor Apoptosis
  3. ROR Apoptosis
  4. XY077

XY077 (compound 14a) 是一种 RORγ 反向激动剂，其 IC50 值为 0.004 μM。XY077 诱导细胞凋亡 (cell apoptosis)，在体内外均显示出抗增殖活性。

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XY077 Chemical Structure

XY077 Chemical Structure

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XY077 相关抗体

Top Publications Citing Use of Products

查看 ROR 亚型特异性产品:

查看所有亚型
RORγ RORα RORβ

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

XY077 (compound 14a) is a RORγ inverse agonist with the IC50 of 0.004 μM. XY077 induces cell apoptosis and shows antiproliferative activity in vivoand in vitro[1].

分子量

580.64

Formula

C27H27F3N2O5S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

XY077 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

XY077XY 077XY-077RORApoptosisRAR-related orphan receptorLNCaPC4-2B22Rv1prostate cancer22Rv1 mice xenograft tumor modelInhibitorinhibitorinhibit

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目录号：
HY-163612
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