ZnAF-1F 

ZnAF-1F is a potent fluorophore for with an K_d value of 2.2 nM. ZnAF-1F can be used as fluorescent probes for Zn²⁺ in cells. ZnAF-1F shows λ excitation of 489 nm and λ emission of 514 nm^[1][2][3].

ZnAF-1F (1 μM) 在 100 mM HEPES 缓冲液中显示 K_on 值为 3.5*10⁶ M^-1s^-1，K_off 值为 7.7*10^-3 s^-1[1]。
ZnAF-1F 是中性及微酸性条件下的 Zn 传感器^[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

608.59

C₃₄H₂₆F₂N₄O₅

443302-08-7

固体

Orange to red

514

489

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

• [1]. Hirano T, et al. Improvement and biological applications of fluorescent probes for zinc, ZnAFs. J Am Chem Soc. 2002 Jun 12;124(23):6555-62.  [Content Brief]

  [2]. Zhaohua Dai, et al. Tailoring tripodal ligands for zinc sensing. New J. Chem., 2007,31, 1708-1718.

  [3]. Que EL, et al. Metals in neurobiology: probing their chemistry and biology with molecular imaging. Chem Rev. 2008 May;108(5):1517-49.  [Content Brief]