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  2. Parasite
  3. β-Carboline-1-propionic acid

β-Carboline-1-propionic acid 是一种可从 Ailanthus altissima 提取的生物碱。β-Carboline-1-propionic acid 可用作抗利什曼胺剂。

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β-Carboline-1-propionic acid Chemical Structure

β-Carboline-1-propionic acid Chemical Structure

CAS No. : 89915-39-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-Carboline-1-propionic acid is a alkaloid which can be extracted from Ailanthus altissima. β-Carboline-1-propionic acid can be used as an antileishmanial agent[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Calu-3 CC50
> 100 μM
Compound: Table 1, R7C2
Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human Calu-3 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
HCT-8 CC50
> 100 μM
Compound: Table 1, R7C2
Cytotoxicity against human HCT-8 cells assessed as redcution in cell viability incubated for 96 hrs by PrestoBlue reagent based assay
Cytotoxicity against human HCT-8 cells assessed as redcution in cell viability incubated for 96 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
HepG2 CC50
> 100 μM
Compound: Table 1, R7C2
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
MCF7 ED50
> 20 μg/mL
Compound: beta-carboline-1-propionicacid
Cytotoxicity against human MCF7 cells by SRB assay
Cytotoxicity against human MCF7 cells by SRB assay
[PMID: 14575431]
MRC5 CC50
> 100 μM
Compound: Table 1, R7C2
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
Vero CC50
> 100 μM
Compound: Table 1, R7C2
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 48 hrs by PrestoBlue reagent based assay
[PMID: 36399766]
分子量

240.26

Formula

C14H12N2O2

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
β-Carboline-1-propionic acid
目录号:
HY-N2926
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