1. 天然产物
  2. 植物 黄酮类
  3. 藤黄科 其他黄酮类
  4. 贯叶连翘
  5. 1,3,5,6-Tetrahydroxyxanthone

1,3,5,6-Tetrahydroxyxanthone 是一种天然的氧杂蒽酮,可从藤黄属 (藤黄科) 分枝中分离得到。1,3,5,6-Tetrahydroxyxanthone 诱导正常血压和高血压大鼠的利尿和尿食盐排泄。

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1,3,5,6-Tetrahydroxyxanthone Chemical Structure

1,3,5,6-Tetrahydroxyxanthone Chemical Structure

CAS No. : 5084-31-1

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

1,3,5,6-Tetrahydroxyxanthone is a natural xanthone that can be isolated from Garcinia achachairu Rusby (Clusiaceae) branches. 1,3,5,6-Tetrahydroxyxanthone induces diuresis and saluresis in normotensive and hypertensive rats[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
10 mg/mL
Compound: 16
Cytotoxicity against human A549 cells after 3 days by SRB assay
Cytotoxicity against human A549 cells after 3 days by SRB assay
[PMID: 15568778]
HCT-116 IC50
18.6 μM
Compound: Table S1, R269C2
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay
[PMID: 30684866]
HeLa S3 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HeLaS3 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HepG2 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HepG2 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
HT-29 IC50
> 10 μM
Compound: 22
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human HT-29 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
KB IC50
> 10 μM
Compound: 22
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
Cytotoxicity in human KB cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
MCF7 IC50
> 10 μM
Compound: 22
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
Cytotoxicity in human MCF7 cells incubated for 72 hrs by MTT assay
[PMID: 30978023]
MCF7 IC50
9.3 mg/mL
Compound: 16
Cytotoxicity against human MCF7 cells after 3 days by SRB assay
Cytotoxicity against human MCF7 cells after 3 days by SRB assay
[PMID: 15568778]
分子量

260.20

Formula

C13H8O6

CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
1,3,5,6-Tetrahydroxyxanthone
目录号:
HY-N9113
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