2. Immunology/Inflammation
  3. COX
  4. COX-2-IN-1

COX-2-IN-1 是 一个强效的 COX-2 抑制剂，其 IC50 值为 3.9 μM。

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COX-2-IN-1 Chemical Structure

COX-2-IN-1 Chemical Structure

CAS No. : 787623-48-7

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规格 价格 是否有货 数量
1 mg ￥2205
1 - 2 周
5 mg   询价  
10 mg   询价  

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Customer Review

COX-2-IN-1 相关抗体

Top Publications Citing Use of Products

查看 COX 亚型特异性产品:

查看所有亚型
COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

COX-2-IN-1 is potent and slective COX-2 inhibitor with an IC50 of 3.9 μM.

IC50 & Target[1]

COX-2

3.9 μM (IC50)

体外研究
(In Vitro)

COX-2-IN-1(compound 5f) is an inhibitor of COX-1 and COX-2 with IC50s of >100 and 3.9 μM, respctively. Comparison of 5b and COX-2-IN-1 shows that smaller halogen atom at 5th position on the indole ring enhances COX-2 enzyme inhibition activity, whereas the presence of a larger bromine atom at 6th position of the ring improves the inhibitory activity (5d, 5e and 5h) of the compound[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

COX-2-IN-1 相关抗体:
分子量

442.84

Formula

C18H14ClF3N4O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

COX-2-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

COX-2-IN-1787623-48-7COXCyclooxygenaseInhibitorinhibitorinhibit

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产品名称：
COX-2-IN-1
目录号：
HY-U00275
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