2. GPCR/G Protein
  3. Prostaglandin Receptor
  4. 11-keto Fluprostenol

11-keto Fluprostenol  (Synonyms: Fluprostenol Prostaglandin D2)

目录号: HY-126911
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摩尔计算器

11-keto Fluprostenol (Fluprostenol Prostaglandin D2)是前列腺素 D2 (PGD2) 的类似物，经过结构改造，可延长其半衰期并提高药效。氟前列醇是经过充分研究的 PGF2α 强效类似物，主要通过 FP 受体起作用。氟前列醇在 C-11 处氧化可生成 11-keto Fluprostenol (Fluprostenol Prostaglandin D2)。与 PGD2 相比，11-keto Fluprostenol (Fluprostenol Prostaglandin D2)与 CRTH2/DP2 受体的结合力适中，而对 DP1 受体基本无活性。

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11-keto Fluprostenol Chemical Structure

11-keto Fluprostenol Chemical Structure

CAS No. : 62145-07-7

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11-keto Fluprostenol 相关抗体

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DP EP FP IP TXA2/TP TXB2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

11-keto Fluprostenol is an analog of prostaglandin D2 (PGD2) with structural modifications intended to give it a prolonged half-life and greater potency. Fluprostenol is a well-studied, potent analog of PGF2α and acts primarily through the FP receptor. Oxidation at C-11 of fluprostenol yields 11-keto fluprostenol. 11-keto Fluprostenol exhibits moderate binding to the CRTH2/DP2 receptor compared to PGD2 and essentially no activity at the DP1 receptor.

分子量

456.45

Formula

C23H27F3O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

11-keto Fluprostenol 相关分类

  • 摩尔计算器

  • 稀释计算器

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Keywords:

11-keto Fluprostenol62145-07-7Fluprostenol Prostaglandin D2Fluprostenol Prostaglandin D 2Fluprostenol Prostaglandin D-2Prostaglandin ReceptorInhibitorinhibitorinhibit

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