2. 天然产物
  3. 疾病研究领域 植物 酚类
  4. 大戟科 其他 单酚类
  5. 大萼升麻桐
  6. 2,3,8-Tri-O-methylellagic acid

2,3,8-Tri-O-methylellagic acid  (Synonyms: 3,3′,4-Tri-O-methylellagic acid)

目录号: HY-N1652
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2,3,8-Tri-O-methylellagic acid 是一种酚类化合物， 可从 Neoboutonia macrocalyx 的茎皮中分离得到。2,3,8-Tri-O-methylellagic acid 的活性是亲本鞣花酸的 50 倍。

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2,3,8-Tri-O-methylellagic acid Chemical Structure

2,3,8-Tri-O-methylellagic acid Chemical Structure

CAS No. : 1617-49-8

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2,3,8-Tri-O-methylellagic acid 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
Col2 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
HT-29 IC50
> 10 μM
Compound: S3
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
[PMID: 30057155]
HT-29 IC50
> 10 μM
Compound: S3
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
KB ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
Lu1 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MCF7 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MDA-MB-435 IC50
> 10 μM
Compound: S3
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
OVCAR-3 IC50
> 10 μM
Compound: S3
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
P388 ED50
> 5 μg/mL
Compound: 10
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
分子量

344.27

Formula

C17H12O8
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

2,3,8-Tri-O-methylellagic acid 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

2,3,8-Tri-O-methylellagic acid1617-49-83,3′,4-Tri-O-methylellagic acidOthersEuphorbiaceaeNeoboutonia macrocalyxTerpenoidsgallic acidellagic acidInhibitorinhibitorinhibit

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