2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK
  3. EGFR
  4. 4-Epidoxycycline

4-Epidoxycycline  (Synonyms: 4-表强力霉素)

目录号: HY-126850
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摩尔计算器

4-Epidoxycycline 是抗生素多西环素 (doxycycline，HY-N0565) 的一种肝脏代谢产物，在小鼠中不具有抗生素功能。4-Epidoxycycline 在体外实验和活体小鼠模型中调控 HER2 基因表达的能力与 doxycycline 相当，在肿瘤组织中也表现出与 doxycycline 类似的高效性，可以实现超过 95% 的肿瘤消退率。

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4-Epidoxycycline Chemical Structure

4-Epidoxycycline Chemical Structure

CAS No. : 6543-77-7

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4-Epidoxycycline 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

4-Epidoxycycline is a liver metabolite of the antibiotic doxycycline (doxycycline, HY-N0565) and doesn't have antibiotic properties in mice. 4-Epidoxycycline’s ability to regulate HER2 gene expression in vitro and in live mouse models is similar to that of doxycycline, and it shows comparable high efficacy in tumor tissues, achieving over 95% tumor regression rates[1].

分子量

444.43

Formula

C22H24N2O8
CAS 号
中文名称

4-表强力霉素
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

4-Epidoxycycline 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Epidoxycycline6543-77-74-表强力霉素EGFREpidermal growth factor receptorErbB-1HER1cancerdoesn't have antibiotic propertiesmiceInhibitorinhibitorinhibit

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