2. 天然产物
  3. 植物 疾病研究领域 萜类
  4. 菊科 其他 伞形科 三萜
  5. 伞序托鞭菊 Lychnophora antillana
  6. 6''-O-Acetylsaikosaponin A

6''-O-Acetylsaikosaponin A 

目录号: HY-N7613 纯度: ≥98.0%
COA 产品使用指南

摩尔计算器

6''-O-Acetylsaikosaponin A，从柴胡根中分离得到的乙酰柴胡皂苷，具有一定的破骨细胞抑制活性。

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6''-O-Acetylsaikosaponin A Chemical Structure

6''-O-Acetylsaikosaponin A Chemical Structure

CAS No. : 64340-46-1

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1 mg ￥2200
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6''-O-Acetylsaikosaponin A 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6''-O-Acetylsaikosaponin A, an acetyl saikosaponin isolated from the roots of Bupleurum chinense, shows some osteoclast-inhibiting activities[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
35.32 μM
Compound: 13
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Bcap37 IC50
34.13 μM
Compound: 13
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
Hep 3B2 IC50
16.93 μM
Compound: 13
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
HepG2 IC50
20.81 μM
Compound: 13
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
MCF7 IC50
36.22 μM
Compound: 13
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay
[PMID: 26259802]
体外研究
(In Vitro)

The major bioactive compounds isolated from R. bupleuri are saikosaponins, which have been proved to possess significant biological activities, including anti-hepatitis, anti-inflammatory, anti-tumor and immunoregulatory effects[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

6''-O-Acetylsaikosaponin A 相关抗体:
分子量

823.02

Formula

C44H70O14
CAS 号
性状

固体

颜色

White to off-white

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (121.50 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 1.2150 mL 6.0752 mL 12.1504 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

6''-O-Acetylsaikosaponin A 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.2150 mL 6.0752 mL 12.1504 mL 30.3759 mL
5 mM 0.2430 mL 1.2150 mL 2.4301 mL 6.0752 mL
10 mM 0.1215 mL 0.6075 mL 1.2150 mL 3.0376 mL
15 mM 0.0810 mL 0.4050 mL 0.8100 mL 2.0251 mL
20 mM 0.0608 mL 0.3038 mL 0.6075 mL 1.5188 mL
25 mM 0.0486 mL 0.2430 mL 0.4860 mL 1.2150 mL
30 mM 0.0405 mL 0.2025 mL 0.4050 mL 1.0125 mL
40 mM 0.0304 mL 0.1519 mL 0.3038 mL 0.7594 mL
50 mM 0.0243 mL 0.1215 mL 0.2430 mL 0.6075 mL
60 mM 0.0203 mL 0.1013 mL 0.2025 mL 0.5063 mL
80 mM 0.0152 mL 0.0759 mL 0.1519 mL 0.3797 mL
100 mM 0.0122 mL 0.0608 mL 0.1215 mL 0.3038 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

6''-O-Acetylsaikosaponin A64340-46-1OthersosteoclastderivativebioactiveacetylsaikosaponinInhibitorinhibitorinhibit

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