2. Others
  3. Others
  4. Dixyrazine

Dixyrazine  (Synonyms: 地西拉嗪)

目录号: HY-U00153 纯度: 99.87%
COA 产品使用指南

摩尔计算器

Dixyrazine 是 Phenothiazine 衍生物，可预防注射硫酸鱼精蛋白引起的脑水肿。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Dixyrazine Chemical Structure

Dixyrazine Chemical Structure

CAS No. : 2470-73-7

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥4704
In-stock
1 mg ￥2400
In-stock
5 mg ￥5000
In-stock
10 mg 现货 询价
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Other Forms of Dixyrazine:

Dixyrazine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.

体内研究
(In Vivo)

Pretreatment with Dixyrazine 10 mg/kg completely prevents the brain oedema and significantly reduces the albumin increase in cerebrospinal fluid (CSF)[1]. The phenothiazine Dixyrazine (5 mg/kg i.v.) has minimal, transient hypotensive effects but significantly reduces the leakage of 126I labelled serum albumin in conscious rats subjected to acute hypertension provoked by i.v. Adrenaline or Bicuculline. The diameters of pial arteries and veins are continuously measured with a multichannel videoangiometer through a closed cranial window in anesthetized rats before and after i.v. injection of Dixyrazine (5 mg/kg). Dixyrazine, 5 mg /kg, induces a slight transitory decrease in blood pressure (10-20 mm Hg). Maximum MAP is slightly but not significantly lower in Dixyrazine-treated rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

427.60

Formula

C24H33N3O2S
CAS 号
性状

固体

颜色

White to off-white

中文名称

地西拉嗪
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (233.86 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.3386 mL 11.6932 mL 23.3863 mL
5 mM 0.4677 mL 2.3386 mL 4.6773 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.87%

COA (191 KB) HNMR (224 KB) LCMS (469 KB)

产品使用指南 (1538 KB)
参考文献
Animal Administration
[2]

Rats[2]
Male Sprague-Dawley rats (200-225 g) are used. Evans blue and 125I-HSA are used as tracers, and controls are compared to rats pretreated with Dixyrazine 5 mL/kg or 15 mg/kg. The lower dose is given 15-20 min before the infusion of urea (that is the same interval as in the hypertension experiments). Because of larger effects on blood pressure with higher doses, the interval has to be extended to 40 min in this group. The radioactivity is determined in the right and left hemisphere and related to the activity in the blood.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Dixyrazine 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3386 mL 11.6932 mL 23.3863 mL 58.4659 mL
5 mM 0.4677 mL 2.3386 mL 4.6773 mL 11.6932 mL
10 mM 0.2339 mL 1.1693 mL 2.3386 mL 5.8466 mL
15 mM 0.1559 mL 0.7795 mL 1.5591 mL 3.8977 mL
20 mM 0.1169 mL 0.5847 mL 1.1693 mL 2.9233 mL
25 mM 0.0935 mL 0.4677 mL 0.9355 mL 2.3386 mL
30 mM 0.0780 mL 0.3898 mL 0.7795 mL 1.9489 mL
40 mM 0.0585 mL 0.2923 mL 0.5847 mL 1.4616 mL
50 mM 0.0468 mL 0.2339 mL 0.4677 mL 1.1693 mL
60 mM 0.0390 mL 0.1949 mL 0.3898 mL 0.9744 mL
80 mM 0.0292 mL 0.1462 mL 0.2923 mL 0.7308 mL
100 mM 0.0234 mL 0.1169 mL 0.2339 mL 0.5847 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dixyrazine2470-73-7地西拉嗪OthersInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Dixyrazine
目录号：
HY-U00153
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z