2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 老药新用化合物库系列
  6. FDA 上市及药典收录化合物库
FDA 上市及药典收录化合物库 - FDA Approved & Pharmacopeial Drug Library

Cat. No.: HY-L066

新药研发是一个耗时且成本高昂的过程。与新药研发相比，药物重定位（也称为老药新用）具有很多优势。老药新用降低了药物研发失败的风险，并且可以缩短研发周期、降低研发成本等。批准上市药物及药典收录产品由于具有良好的生物活性、药代动力学特性和安全性，特别适合老药新用的研究。

MCE 收录了 3,589 个由 FDA、EMA、NMPA、PMDA 等各国药监局批准上市药物及美国药典、日本药典、英国药典等药典收录的化合物，这些化合物具有良好的生物活性、安全性和生物利用度。FDA 上市及药典收录化合物库是一种很好的药物再利用工具，可以显著加快药物开发进程。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE FDA 上市及药典收录化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，3,498 个产品以 10 mM 浓度提供，65 个产品以 2 mM 浓度提供，26 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 3,589 marketed drugs for high throughput screening (HTS) and high content screening (HCS).

•   All drugs were from approved institutions such as FDA, EMA, NMPA, PMDA, or pharmacopoeia such as USP, BP, EP, JP, etc.

•   Used in the research of oncology, cardiology, anti-inflammatory, immunology, dermatology, endocrinology, neurology, and more.

•   A useful tool for researching new targets of marketed old drugs.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 3,589 marketed and pharmacopeial drugs compounds supplied as pre-dissolved Solutions or Solid
Solution: 3,498 compounds supplied in 10 mM solution, 65 compounds supplied in 2 mM solution, 26 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

Fungal (110)

COX (104)

HIV (95)

mAChR (77)

VEGFR (37)

HCV (35)

EGFR (33)

HSV (33)

iGluR (33)

nAChR (30)

HBV (27)

PDGFR (25)

JAK (24)

PPAR (24)

FGFR (23)

MMP (22)

Akt (21)

c-Kit (21)

STAT (20)

PI3K (17)

ERK (16)

AMPK (15)

PARP (15)

PKC (15)

CDK (14)

HDAC (13)

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定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    FDA Approved & Pharmacopeial Drug Library
    目录号：
    HY-L066
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