2. Anti-infection
  3. Fungal Bacterial Antibiotic
  4. Kanosamine hydrochloride

Kanosamine hydrochloride 

目录号: HY-112176 纯度: ≥99.0%
COA 产品使用指南

摩尔计算器

Kanosamine hydrochloride是一种抗生素，可抑制植物病原卵菌，某些真菌 (fungi) 和细菌 (bacterial) 的生长。Kanosamine抑制 Phytophthora medicaginis M2913 和 Aphanomyces euteiches WI-98的MIC 分别为25 和 60 μg/mL。

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Kanosamine hydrochloride Chemical Structure

Kanosamine hydrochloride Chemical Structure

CAS No. : 57649-10-2

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规格 价格 是否有货 数量
1 mg ￥1440
In-stock
5 mg ￥4365
In-stock
10 mg   询价  
50 mg   询价  

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Customer Review

Other Forms of Kanosamine hydrochloride:

Kanosamine hydrochloride 相关抗体

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  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain fungi and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 μg/mL, respectively.

IC50 & Target

MIC: 25 µg/mL (Phytophthora medicaginis M2913), 60 µg/mL (Aphanomyces euteiches WI-98)[1]
体外研究
(In Vitro)

Kanosamine is highly inhibitory to growth of plant-pathogenic oomycetes. Among the strains tested, Phytophthora medicaginis M2913 is the most sensitive to kanosamine, whereas Pythium aphanidermatum Pa138 and Pythium torulosum A25a are less sensitive, and Aphanomyces euteiches WI-98 shows an intermediate level of sensitivity. The oomycetes are more sensitive to kanosamine at pH 7.0 than at pH 5.6. Kanosamine inhibits few bacterial species. Kanosamine is moderately inhibitory to certain fungi. All of the fungi and oomycetes inhibited by kanosamine are pathogens of plants. Maximum accumulation of kanosamine in B. cereus UW85 culture supernatants coincided with sporulation. Kanosamine accumulation is enhanced by the addition of ferric iron and suppressed by addition of phosphate to rich medium. Kanosamine accumulation is also enhanced more than 300% by the addition of alfalfa seedling exudate to minimal medium[1]. The antibiotic kanosamine inhibits growth of Saccharomyces cerevisiae and a range of human pathogenic fungi, including Candida albicans. The action of kanosamine on C. albicans cells results in profound morphological changes, inhibition of septum formation and cell agglutination[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Kanosamine hydrochloride 相关抗体:
分子量

215.63

Formula

C6H14ClNO5
CAS 号
性状

固体

颜色

White to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

DMF 中的溶解度 : 25 mg/mL (115.94 mM; 超声加热助溶)

DMSO 中的溶解度 : 25 mg/mL (115.94 mM; 超声加热助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.6376 mL 23.1879 mL 46.3757 mL
5 mM 0.9275 mL 4.6376 mL 9.2751 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: ≥99.0%

COA (287 KB)

产品使用指南 (1538 KB)
参考文献
Cell Assay
[1]

MICs are determined by a serial dilution microtitrer plates method in Yeast Nitrogen Base medium containing 1% glucose or glycerol as a carbon source. Wells containing serially diluted kanosamine and control wells are inoculated with 105 cells /mL of an overnight culture of fungal cells and incubated for 24 h at 30°C. MIC is defined as the lowest antifungal agent concentration preventing visible growth. Alternatively, MICs are determined in RPMI 1640 medium buffered with 3-[N-morpholino]propanesulphonic acid (MOPS) to pH 7, under conditions recommended by NCCLS. In all cases, reproducible sharp end points are obtained and trailing effects are not observed[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Kanosamine hydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMF / DMSO 1 mM 4.6376 mL 23.1879 mL 46.3757 mL 115.9393 mL
5 mM 0.9275 mL 4.6376 mL 9.2751 mL 23.1879 mL
10 mM 0.4638 mL 2.3188 mL 4.6376 mL 11.5939 mL
15 mM 0.3092 mL 1.5459 mL 3.0917 mL 7.7293 mL
20 mM 0.2319 mL 1.1594 mL 2.3188 mL 5.7970 mL
25 mM 0.1855 mL 0.9275 mL 1.8550 mL 4.6376 mL
30 mM 0.1546 mL 0.7729 mL 1.5459 mL 3.8646 mL
40 mM 0.1159 mL 0.5797 mL 1.1594 mL 2.8985 mL
50 mM 0.0928 mL 0.4638 mL 0.9275 mL 2.3188 mL
60 mM 0.0773 mL 0.3865 mL 0.7729 mL 1.9323 mL
80 mM 0.0580 mL 0.2898 mL 0.5797 mL 1.4492 mL
100 mM 0.0464 mL 0.2319 mL 0.4638 mL 1.1594 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kanosamine57649-10-2FungalBacterialAntibioticInhibitorinhibitorinhibit

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目录号：
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