2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗细菌化合物库
抗细菌化合物库 - Antibacterial Compound Library

Cat. No.: HY-L049

抗菌剂是一类具有灭菌活性的化合物，通过杀灭或降低细菌的代谢活性，降低其在机体中的致病性。抗菌药物主要作用于细菌细胞壁合成、蛋白质合成、DNA 复制和代谢途径等方面。然而，对抗菌药物的耐药性已成为世界范围内感染疾病高发病率和死亡率的主要原因。耐药的主要机制包括药物摄取受限、药物靶点改变、药物失活和药物活性外排等。因此，迫切需要开发针对耐药生物的新的抗菌药物。

MCE 提供 1,407 种具有明确抗细菌活性的化合物，MCE 抗细菌化合物库是药物再利用，联合给药研究及生物学研究的有用工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗细菌化合物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，1,356 个产品以 10 mM 浓度提供，35 个产品以 2 mM 浓度提供，16 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 1,407 bioactive anti-bacterial compounds for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of anti-bacterial drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 1,407 anti-bacterial compounds supplied as pre-dissolved Solutions or Solid
Solution: 1,356 compounds supplied in 10 mM solution, 35 compounds supplied in 2 mM solution, 16 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

Fungal (117)

HIV (16)

HSV (13)

MMP (10)

COX (9)

PPAR (8)

Akt (6)

PI3K (6)

STAT (6)

AMPK (5)

HBV (5)

HSP (5)

mTOR (5)

Wnt (5)

ERK (4)

PKC (4)

EGFR (3)

FKBP (3)

IKK (3)

JNK (3)

AP-1 (2)

相关服务推荐
定制您专属的化合物库
  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Antibacterial Compound Library
    目录号：
    HY-L049
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