2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. Sultopride hydrochloride

Sultopride hydrochloride  (Synonyms: 盐酸舒必利; LIN-1418 hydrochloride)

目录号: HY-42849A 纯度: 99.92%
COA 产品使用指南

摩尔计算器

Sultopride hydrochloride (LIN-1418 hydrochloride) 是多巴胺 D2 受体的选择性拮抗剂。

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Sultopride hydrochloride Chemical Structure

Sultopride hydrochloride Chemical Structure

CAS No. : 23694-17-9

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规格 价格 是否有货 数量
10 mM * 1 mL in Water ￥1100
In-stock
1 mg ￥420
In-stock
5 mg ￥1000
In-stock
10 mg ￥1600
In-stock
25 mg ￥3200
In-stock
50 mg ￥5100
In-stock
100 mg 现货 询价
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

Customer Review

Other Forms of Sultopride hydrochloride:

Sultopride hydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

  • 生物活性

  • 实验参考方法

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.

IC50 & Target

Dopamine D2 receptor[1]
体内研究
(In Vivo)

Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride hydrochloride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride hydrochloride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride hydrochloride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride hydrochloride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

390.93

Formula

C17H27ClN2O4S
CAS 号
性状

固体

颜色

White to off-white

中文名称

盐酸舒必利
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 50 mg/mL (127.90 mM; 超声助溶)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 2.5580 mL 12.7900 mL 25.5800 mL
5 mM 0.5116 mL 2.5580 mL 5.1160 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物实验：

以下溶解方案，请直接配制工作液。建议现用现配，在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比； 如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶。

  • 方案 一

    请依序添加每种溶剂： PBS

    Solubility: 140 mg/mL (358.12 mM); 澄清溶液; 超声助溶

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献
Animal Administration
[1]

Thirty-six male Sprague-Dawley rats weighing 180 to 220 g are used in this study. The rats are divided into three groups of 6 each. One group is intraperitoneally injected with Sultopride hydrochloride (100 mg/kg body weight), the second group with sulphide (100 mg/kg body weight), and the third group with normal saline. One hundred minutes after the initial treatments, apomorphine (0.1 mg/kg body weight, dissolved in saline ad libitum) is administered subcutaneously to the three groups, and 20 minutes later the rats are sacrificed. The third group serves as controls[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献

Sultopride hydrochloride 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.5580 mL 12.7900 mL 25.5800 mL 63.9501 mL
5 mM 0.5116 mL 2.5580 mL 5.1160 mL 12.7900 mL
10 mM 0.2558 mL 1.2790 mL 2.5580 mL 6.3950 mL
15 mM 0.1705 mL 0.8527 mL 1.7053 mL 4.2633 mL
20 mM 0.1279 mL 0.6395 mL 1.2790 mL 3.1975 mL
25 mM 0.1023 mL 0.5116 mL 1.0232 mL 2.5580 mL
30 mM 0.0853 mL 0.4263 mL 0.8527 mL 2.1317 mL
40 mM 0.0640 mL 0.3198 mL 0.6395 mL 1.5988 mL
50 mM 0.0512 mL 0.2558 mL 0.5116 mL 1.2790 mL
60 mM 0.0426 mL 0.2132 mL 0.4263 mL 1.0658 mL
80 mM 0.0320 mL 0.1599 mL 0.3198 mL 0.7994 mL
100 mM 0.0256 mL 0.1279 mL 0.2558 mL 0.6395 mL

* 备注：如您选择水作为储备液，请稀释至工作液后，再用 0.22 μm 的滤膜过滤除菌后使用。

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sultopride23694-17-9LIN-1418盐酸舒必利LIN1418LIN 1418Dopamine ReceptordopamineD2receptorDOPACHVAlevelsstriatumInhibitorinhibitorinhibit

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